Supor (PES) Capsule Filters - 12093
Backed by comprehensive manufacturer validation data, Supor PES capsule filters support the documentation requirements of pharmaceutical and biotechnology production environments. Building on this foundation, Supor membrane technology within the capsule housing achieves ultra-low protein adsorption levels that preserve biologics throughout sterile filtration, supported by drug master file registrations and extensive biocompatibility data. The outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.
Key Supor (PES) Membrane Characteristics
- Non-sterile capsule delivery is appropriate for clarification, prefiltration, and general laboratory applications where the filtrate does not require sterility assurance.
- Internal holdup volume of 6 milliliters minimizes sample loss during capsule filtration, a critical consideration when processing expensive biologics or limited-volume preparations.
- Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14, supporting diverse pharmaceutical processing applications within a single membrane platform.
- The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
- Rated for operating pressures up to 60 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.
Key Capsule Construction Features
- Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
- Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. For biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.
Sterilization Guidance
Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 51 psi
- Burst Pressure (psi)
- 60 psi
- Capsule Format
- AcroPak 200
- Compliance Standards
- USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Polypropylene
- Diameter
- 10.5 cm
- Filling Bell (Yes/ No)
- Yes
- Filtration Area
- 200 cm²
- Flow Rate
- 0.3 L/min at 0.1 bar
- Holdup Volume
- 6 mL
- Inlet Connection
- 1/4 to 1/2 in. stepped hose barb
- Length
- 10.1 cm
- Material
- PES
- Max Batch Volume
- 20 L
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 60 °C
- Membrane Brand
- Supor
- Outlet Connection
- 1/4 to 1/2 in. stepped hose barb with filling bell
- Pack Count
- 3
- Pore Size (µm)
- 0.2
- Pre-filter Pore Size
- 0.8
- Prefilter (Yes/No)
- Yes
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- Yes
- Wettability
- Hydrophilic
- Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
- Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
- Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
- Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
- Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
- Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.