AcroPak 200 Capsules w/ Supor EKV Membrane - 0.2um, 13mm (3/Pkg) SKU: 12095

Supor (PES) Capsule Filters - 12095

The asymmetric pore structure of Supor PES membranes captures contaminants at the surface while maintaining open channels beneath, delivering high flow rates and dirt-holding capacity. Equally important, the Supor PES membrane platform scales consistently from laboratory evaluation through production implementation, with capsule effective filtration areas ranging from bench-scale to large-batch formats. The outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Supor (PES) Membrane Characteristics

• Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14, supporting diverse pharmaceutical processing applications within a single membrane platform.
• Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
• Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
• The 60 degree Celsius temperature limit ensures reliable capsule performance for ambient and moderately heated filtration applications.
• Capsule holdup volume of 6 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.

Key Capsule Construction Features

• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• Sanitary flange fittings meet the dimensional and surface finish standards required by pharmaceutical process piping systems, supporting clean-in-place and sterilize-in-place protocols.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.

As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. For biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

Sterilization Guidance

Polypropylene construction throughout the device permits autoclave sterilization at standard conditions, enabling end-user preparation for sterile filtration applications as needed.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

48 psi

Burst Pressure (psi)

60 psi

Capsule Format

AcroPak 200

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Diameter

6.7 cm

Filling Bell (Yes/ No)

No

Filtration Area

200 cm²

Flow Rate

0.241 L/min at 0.1 bar

Holdup Volume

≤6 mL

Inlet Connection

13mm (1/2 in.) sanitary flange

Length

7.3 cm

Material

PES

Max Batch Volume

20 L

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

60 °C

Membrane Brand

Supor EKV

Outlet Connection

13mm (1/2 in.) sanitary flange

Pack Count

3

Pore Size (µm)

0.2

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
• Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
• Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.