Supor (PES) Capsule Filters - 12202
Supor PES capsule filters combine asymmetric membrane architecture with ultra-low protein adsorption, maximizing throughput while preserving the biological activity of filtered solutions. Optimized for laboratory use, the Supor PES membrane platform scales consistently from laboratory evaluation through production implementation, with capsule effective filtration areas ranging from bench-scale to large-batch formats. In sum, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.
Key Supor (PES) Membrane Characteristics
- The prefilter-final filter combination within a single capsule housing provides graduated retention that extends device life when processing biological fluids with variable particulate loads.
- Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
- Maximum operating pressure of 60 psi provides the differential pressure capacity needed for sustained filtration of viscous solutions and high-flow process streams.
- The asymmetric Supor membrane structure maximizes dirt-holding capacity and flow rates, delivering throughput performance that reduces the number of capsule devices required per batch.
- The 60 degree Celsius temperature limit ensures reliable capsule performance for ambient and moderately heated filtration applications.
Key Capsule Construction Features
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
- Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
- Hose barb connections enable direct integration with flexible tubing systems commonly used in laboratory and pilot-scale filtration setups.
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. If your pharmaceutical process requires validated filtration performance with comprehensive regulatory documentation, Supor PES capsule filters provide the performance data and quality certifications your filing depends on. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.
Sterilization Guidance
Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 51 psi
- Burst Pressure (psi)
- 60 psi
- Capsule Format
- AcroPak 20
- Compliance Standards
- USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Polypropylene
- Diameter
- 6.7 cm
- Filling Bell (Yes/ No)
- Yes
- Filtration Area
- 20 cm²
- Flow Rate
- 0.028 L/min at 0.1 bar
- Holdup Volume
- ≤2.5 mL
- Inlet Connection
- 1/4 to 1/2 in. stepped hose barb with female luer slip
- Length
- 8.3 cm
- Material
- PES
- Max Batch Volume
- 20 L
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 60 °C
- Membrane Brand
- Supor
- Outlet Connection
- 1/4 to 1/2 in. stepped hose barb with filling bell
- Pack Count
- 3
- Pore Size (µm)
- 0.2
- Pre-filter Pore Size
- 0.8
- Prefilter (Yes/No)
- Yes
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- Yes
- Wettability
- Hydrophilic
- Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
- Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
- Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
- Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
- Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
- Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.