AcroPak 20 Filters w/ Supor Membrane - 0.8/0.2um, Gamma-Irradiated , w/ Filling Bell (3/Pkg) SKU: 12203

Supor (PES) Capsule Filters - 12203

Comprehensive manufacturer documentation and quality system traceability position Supor PES capsule filters for integration into regulated pharmaceutical manufacturing workflows. Supor membrane technology within the capsule housing achieves ultra-low protein adsorption levels that preserve biologics throughout sterile filtration, supported by drug master file registrations and extensive biocompatibility data. To this end, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Supor (PES) Membrane Characteristics

• The asymmetric Supor membrane structure maximizes dirt-holding capacity and flow rates, delivering throughput performance that reduces the number of capsule devices required per batch.
• Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
• Capsule holdup volume of 2.5 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.
• The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
• Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.

Key Capsule Construction Features

• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
• Stepped hose barb connections accommodate tubing with inner diameters from 1/4 to 1/2 inch, providing secure push-fit attachment without requiring clamps or specialized fittings.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.

Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. Under these conditions, for biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

Sterilization Guidance

Polypropylene construction throughout the device permits autoclave sterilization at standard conditions, enabling end-user preparation for sterile filtration applications as needed.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

51 psi

Burst Pressure (psi)

60 psi

Capsule Format

AcroPak 20

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Diameter

6.7 cm

Filling Bell (Yes/ No)

Yes

Filtration Area

20 cm²

Flow Rate

0.028 L/min at 0.1 bar

Holdup Volume

≤2.5 mL

Inlet Connection

1/4 to 1/2 in. stepped hose barb with female luer slip

Length

8.3 cm

Material

PES

Max Batch Volume

20 L

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

60 °C

Membrane Brand

Supor

Outlet Connection

1/4 to 1/2 in. stepped hose barb with filling bell

Pack Count

3

Pore Size (µm)

0.2

Pre-filter Pore Size

0.8

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
• Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.
• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
• Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.