AcroPak 20 Filters w/ Supor EKV Membrane - 0.2um, Gamma-Irradiated , 3/Pk SKU: 12247

Supor (PES) Capsule Filters - 12247

Backed by extensive pharmaceutical validation data, Supor PES capsule filters provide the retention assurance and low-binding performance demanded by regulated manufacturing processes. The Supor PES membrane's asymmetric pore architecture delivers industry-leading flow rates and throughput capacity in a validated sterilizing-grade format backed by comprehensive pharmaceutical documentation packages. On this basis, the result is a filtration process that eliminates cleaning validation, reduces changeover time, and provides batch-to-batch consistency through factory-tested, integrity-verified devices.

Key Supor (PES) Membrane Characteristics

• The 60 psi maximum pressure rating accommodates the differential pressures generated during filtration of particle-laden solutions as the membrane progressively loads.
• Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
• The asymmetric Supor membrane structure maximizes dirt-holding capacity and flow rates, delivering throughput performance that reduces the number of capsule devices required per batch.
• Rated for continuous operation at temperatures up to 60 degrees Celsius, the capsule maintains structural integrity and retention performance across the normal process temperature range.
• Capsule holdup volume of 2.5 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.

Key Capsule Construction Features

• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Stepped hose barb connections accommodate tubing with inner diameters from 1/4 to 1/2 inch, providing secure push-fit attachment without requiring clamps or specialized fittings.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.

From method development through scale-up to production, your capsule filter choice defines the balance between membrane performance, process integration, and the regulatory documentation trail that supports each filtration event. In these cases, for biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

48 psi

Burst Pressure (psi)

60 psi

Capsule Format

AcroPak 20

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Diameter

6.7 cm

Filling Bell (Yes/ No)

Yes

Filtration Area

20 cm²

Holdup Volume

≤2.5 mL

Inlet Connection

1/4 to 1/2 in. stepped hose barb with female luer slip

Length

8.3 cm

Material

PES

Max Batch Volume

20 L

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

60 °C

Membrane Brand

Supor EKV

Outlet Connection

1/4 to 1/2 in. stepped hose barb with filling bell

Pack Count

3

Pore Size (µm)

0.2

Pre-filter Pore Size

0.65

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
• Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.
• Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.