AcroPak 800 Capsules w/ Supor EKV Membrane - 0.2um, 2.5 - 3.8cm, Gamma-Irradiated , 1/Pk SKU: 12463

Supor (PES) Capsule Filters - 12463

Supor PES capsule filters combine asymmetric membrane architecture with ultra-low protein adsorption, maximizing throughput while preserving the biological activity of filtered solutions. Complementing this, Supor membrane technology within the capsule housing achieves ultra-low protein adsorption levels that preserve biologics throughout sterile filtration, supported by drug master file registrations and extensive biocompatibility data. As designed, the outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.

Key Supor (PES) Membrane Characteristics

• Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
• Supor capsule devices are constructed from materials with documented biocompatibility and low extractable characteristics suitable for pharmaceutical manufacturing processes.
• Maximum operating temperature of 40 degrees Celsius supports filtration of warm solutions and accommodates the thermal conditions present in process environments.
• Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
• The 75 psi maximum pressure rating accommodates the differential pressures generated during filtration of particle-laden solutions as the membrane progressively loads.

Key Capsule Construction Features

• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• Tri-clamp compatible sanitary connections enable tool-free capsule installation and removal, minimizing changeover time in production-scale filtration operations.

From method development through scale-up to production, your capsule filter choice defines the balance between membrane performance, process integration, and the regulatory documentation trail that supports each filtration event. For biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

Sterilization Guidance

Polypropylene construction throughout the device permits autoclave sterilization at standard conditions, enabling end-user preparation for sterile filtration applications as needed.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

48 psi

Burst Pressure (psi)

75 psi

Capsule Format

AcroPak 800

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Filling Bell (Yes/ No)

No

Filtration Area

750 cm²

Flow Rate

1.5 L/min

Inlet Connection

1 to 1-1/2 in. sanitary flange

Material

PES

Max Batch Volume

Large-volume batch processing

Maximum Operating Pressure

75 psi

Maximum Operating Temperature (°C)

40 °C

Membrane Brand

Supor EKV

Outlet Connection

1 to 1-1/2 in. sanitary flange

Pack Count

1

Pore Size (µm)

0.2

Pre-filter Pore Size

0.65

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
• Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.
• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.