Supor (PES) Capsule Filters - 12464
Backed by extensive pharmaceutical validation data, Supor PES capsule filters provide the retention assurance and low-binding performance demanded by regulated manufacturing processes. On the performance side, Supor membrane technology within the capsule housing achieves ultra-low protein adsorption levels that preserve biologics throughout sterile filtration, supported by drug master file registrations and extensive biocompatibility data. By design, the result is a filtration process that eliminates cleaning validation, reduces changeover time, and provides batch-to-batch consistency through factory-tested, integrity-verified devices.
Key Supor (PES) Membrane Characteristics
- Maximum operating pressure of 75 psi provides the differential pressure capacity needed for sustained filtration of viscous solutions and high-flow process streams.
- Maximum operating temperature of 40 degrees Celsius supports filtration of warm solutions and accommodates the thermal conditions present in process environments.
- The asymmetric Supor membrane structure maximizes dirt-holding capacity and flow rates, delivering throughput performance that reduces the number of capsule devices required per batch.
- The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
- Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
Key Capsule Construction Features
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
- Barbed inlet and outlet connections provide a practical, leak-resistant interface for gravity-feed, peristaltic pump, and pressure-driven filtration systems using flexible tubing.
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. To address this, for biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.
Sterilization Guidance
Non-sterile delivery accommodates applications where sterility is not required, while the all-polypropylene construction provides the option for autoclave sterilization when aseptic processing is specified.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 48 psi
- Burst Pressure (psi)
- 75 psi
- Capsule Format
- AcroPak 800
- Compliance Standards
- USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Polypropylene
- Filling Bell (Yes/ No)
- Yes
- Filtration Area
- 750 cm²
- Flow Rate
- 1.5 L/min
- Inlet Connection
- 13mm (1/2 in.) hose barb
- Material
- PES
- Max Batch Volume
- Large-volume batch processing
- Maximum Operating Pressure
- 75 psi
- Maximum Operating Temperature (°C)
- 40 °C
- Membrane Brand
- Supor EKV
- Outlet Connection
- 13mm (1/2 in.) hose barb
- Pack Count
- 1
- Pore Size (µm)
- 0.2
- Pre-filter Pore Size
- 0.65
- Prefilter (Yes/No)
- Yes
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- Yes
- Wettability
- Hydrophilic
- Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
- Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
- Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
- Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
- Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.
- Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.