AcroPak 1500 Capsules w/ Supor EKV Membrane - 0.2um, 2.5 - 3.8cm, Gamma-Irradiated , 1/Pk SKU: 12466

Supor (PES) Capsule Filters - 12466

Supor PES capsule filters provide consistent membrane performance from laboratory evaluation through pilot and full production batch volumes within a single validated platform. The Supor PES membrane's asymmetric pore architecture delivers industry-leading flow rates and throughput capacity in a validated sterilizing-grade format backed by comprehensive pharmaceutical documentation packages. By design, the outcome is simplified regulatory documentation and reduced contamination risk, with each single-use capsule providing a validated, traceable filtration event.

Key Supor (PES) Membrane Characteristics

• Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
• The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
• The 40 degree Celsius temperature limit ensures reliable capsule performance for ambient and moderately heated filtration applications.
• The asymmetric Supor membrane structure maximizes dirt-holding capacity and flow rates, delivering throughput performance that reduces the number of capsule devices required per batch.
• Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.

Key Capsule Construction Features

• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• Sanitary flange connections provide the tri-clamp compatible interface required for integration into pharmaceutical and biopharmaceutical process piping systems.

As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. For this application, for biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Non-sterile delivery accommodates applications where sterility is not required, while the all-polypropylene construction provides the option for autoclave sterilization when aseptic processing is specified.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

48 psi

Burst Pressure (psi)

75 psi

Capsule Format

AcroPak 1500

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Filling Bell (Yes/ No)

No

Filtration Area

1500 cm²

Flow Rate

3.2 L/min

Inlet Connection

1 to 1-1/2 in. sanitary flange

Length

22.9 cm

Material

PES

Max Batch Volume

150 L

Maximum Operating Pressure

75 psi

Maximum Operating Temperature (°C)

40 °C

Membrane Brand

Supor EKV

Outlet Connection

1 to 1-1/2 in. sanitary flange

Pack Count

1

Pore Size (µm)

0.2

Pre-filter Pore Size

0.65

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
• Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.
• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
• Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.