AcroPak 500 Capsules w/ Supor Membrane - 0.8/0.2um, Gamma-Irradiated , 1/Pk SKU: 12991

Supor (PES) Capsule Filters - 12991

Supor PES capsule filters provide consistent membrane performance from laboratory evaluation through pilot and full production batch volumes within a single validated platform. Furthermore, Supor membrane technology within the capsule housing achieves ultra-low protein adsorption levels that preserve biologics throughout sterile filtration, supported by drug master file registrations and extensive biocompatibility data. The result is a filtration process that eliminates cleaning validation, reduces changeover time, and provides batch-to-batch consistency through factory-tested, integrity-verified devices.

Key Supor (PES) Membrane Characteristics

The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
The asymmetric Supor membrane structure maximizes dirt-holding capacity and flow rates, delivering throughput performance that reduces the number of capsule devices required per batch.
Rated for continuous operation at temperatures up to 60 degrees Celsius, the capsule maintains structural integrity and retention performance across the normal process temperature range.
Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.

Key Capsule Construction Features

Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.

Whether your process requires sterilizing-grade retention for a 500-milliliter bench trial or clarification capacity for a 100-liter production batch, the right capsule filter configuration eliminates the compromises between throughput, retention, and operational simplicity. For this application, if your pharmaceutical process requires validated filtration performance with comprehensive regulatory documentation, Supor PES capsule filters provide the performance data and quality certifications your filing depends on. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

Sterilization Guidance

Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.