Supor (PES) Capsule Filters - 12993
Backed by comprehensive manufacturer validation data, Supor PES capsule filters support the documentation requirements of pharmaceutical and biotechnology production environments. In addition, the Supor PES membrane's asymmetric pore architecture delivers industry-leading flow rates and throughput capacity in a validated sterilizing-grade format backed by comprehensive pharmaceutical documentation packages. As designed, the outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.
Key Supor (PES) Membrane Characteristics
- Supor capsule devices are constructed from materials with documented biocompatibility and low extractable characteristics suitable for pharmaceutical manufacturing processes.
- The 60 degree Celsius temperature limit ensures reliable capsule performance for ambient and moderately heated filtration applications.
- Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14, supporting diverse pharmaceutical processing applications within a single membrane platform.
- The prefilter-final filter combination within a single capsule housing provides graduated retention that extends device life when processing biological fluids with variable particulate loads.
- Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
Key Capsule Construction Features
- Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
- Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
- Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. To address this, for biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.
Sterilization Guidance
Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 24 psi
- Burst Pressure (psi)
- 60 psi
- Capsule Format
- AcroPak 500
- Compliance Standards
- USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Polypropylene
- Filling Bell (Yes/ No)
- Yes
- Filtration Area
- 500 cm²
- Flow Rate
- 1.3 L/min at 0.1 bar
- Inlet Connection
- 1/4 to 1/2 in. stepped hose barb
- Length
- 14.5 cm
- Material
- PES
- Max Batch Volume
- 50 L
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 60 °C
- Membrane Brand
- Supor
- Outlet Connection
- 1/4 to 1/2 in. stepped hose barb with filling bell
- Pack Count
- 1
- Pore Size (µm)
- 0.45
- Pre-filter Pore Size
- 0.8
- Prefilter (Yes/No)
- Yes
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- Yes
- Wettability
- Hydrophilic
- Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
- Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
- Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
- Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
- Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.
- Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.