Supor (PES) Capsule Filters - 12994
The asymmetric pore structure of Supor PES membranes captures contaminants at the surface while maintaining open channels beneath, delivering high flow rates and dirt-holding capacity. The Supor PES membrane's asymmetric pore architecture delivers industry-leading flow rates and throughput capacity in a validated sterilizing-grade format backed by comprehensive pharmaceutical documentation packages. Because of this, the outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.
Key Supor (PES) Membrane Characteristics
- An integrated prefilter layer upstream of the final membrane captures coarse particulates before they reach the sterilizing-grade surface, extending capsule throughput and service life.
- Supor capsule devices are constructed from materials with documented biocompatibility and low extractable characteristics suitable for pharmaceutical manufacturing processes.
- The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
- Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14, supporting diverse pharmaceutical processing applications within a single membrane platform.
- Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
Key Capsule Construction Features
- Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
- Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. For biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.
Sterilization Guidance
Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 24 psi
- Burst Pressure (psi)
- 60 psi
- Capsule Format
- AcroPak 1000
- Compliance Standards
- USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Polypropylene
- Filling Bell (Yes/ No)
- Yes
- Filtration Area
- 1000 cm²
- Flow Rate
- 2.5 L/min at 0.1 bar
- Inlet Connection
- 1/4 to 1/2 in. stepped hose barb
- Length
- 19.3 cm
- Material
- PES
- Max Batch Volume
- 100 L
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 60 °C
- Membrane Brand
- Supor
- Outlet Connection
- 1/4 to 1/2 in. stepped hose barb with filling bell
- Pack Count
- 1
- Pore Size (µm)
- 0.45
- Pre-filter Pore Size
- 0.8
- Prefilter (Yes/No)
- Yes
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- Yes
- Wettability
- Hydrophilic
- Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
- Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
- Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
- Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
- Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
- Validation Support - Comprehensive manufacturer documentation including extractable profiles and bacterial challenge test data supports integration into regulated processes.