AcroPak 500 Capsules w/ Supor Membrane - 0.2/0.2um, Gamma-Irradiated , 1/Pk SKU: 12995

Supor (PES) Capsule Filters - 12995

Comprehensive manufacturer documentation and quality system traceability position Supor PES capsule filters for integration into regulated pharmaceutical manufacturing workflows. Building on this foundation, the Supor PES membrane platform scales consistently from laboratory evaluation through production implementation, with capsule effective filtration areas ranging from bench-scale to large-batch formats. The result is a filtration workflow that scales efficiently from method development through production, delivering consistent retention performance across the full range of capsule effective filtration areas.

Key Supor (PES) Membrane Characteristics

• Maximum operating pressure of 60 psi provides the differential pressure capacity needed for sustained filtration of viscous solutions and high-flow process streams.
• Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14, supporting diverse pharmaceutical processing applications within a single membrane platform.
• Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
• Supor capsule devices are constructed from materials with documented biocompatibility and low extractable characteristics suitable for pharmaceutical manufacturing processes.
• An integrated prefilter layer upstream of the final membrane captures coarse particulates before they reach the sterilizing-grade surface, extending capsule throughput and service life.

Key Capsule Construction Features

• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.

As single-use filtration continues to replace reusable housings across pharmaceutical and laboratory environments, your capsule filter selection determines both the quality of the filtrate and the efficiency of the workflow. In this context, for biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

51 psi

Burst Pressure (psi)

60 psi

Capsule Format

AcroPak 500

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Filling Bell (Yes/ No)

Yes

Filtration Area

500 cm²

Flow Rate

0.6 L/min at 0.1 bar

Inlet Connection

1/4 to 1/2 in. stepped hose barb

Length

14.5 cm

Material

PES

Max Batch Volume

50 L

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

60 °C

Membrane Brand

Supor

Outlet Connection

1/4 to 1/2 in. stepped hose barb with filling bell

Pack Count

1

Pore Size (µm)

0.2

Pre-filter Pore Size

0.2

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
• Validation Support - Manufacturer documentation including extractable profiles and bacterial challenge data supports regulated process integration.
• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
• Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.