Supor (PES) Capsule Filters - 12996
Supor PES capsule filters provide consistent membrane performance from laboratory evaluation through pilot and full production batch volumes within a single validated platform. Built for consistent results, the Supor PES membrane platform scales consistently from laboratory evaluation through production implementation, with capsule effective filtration areas ranging from bench-scale to large-batch formats. The result is a filtration workflow that scales efficiently from method development through production, delivering consistent retention performance across the full range of capsule effective filtration areas.
Key Supor (PES) Membrane Characteristics
- Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
- The 60 psi maximum pressure rating accommodates the differential pressures generated during filtration of particle-laden solutions as the membrane progressively loads.
- Rated for continuous operation at temperatures up to 60 degrees Celsius, the capsule maintains structural integrity and retention performance across the normal process temperature range.
- Non-sterile configuration accommodates laboratory and industrial applications where the capsule filter serves a clarification or protection function rather than a sterilizing-grade barrier role.
- The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
Key Capsule Construction Features
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
- Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
- Barbed inlet and outlet connections provide a practical, leak-resistant interface for gravity-feed, peristaltic pump, and pressure-driven filtration systems using flexible tubing.
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. If your pharmaceutical process requires validated filtration performance with comprehensive regulatory documentation, Supor PES capsule filters provide the performance data and quality certifications your filing depends on. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.
Sterilization Guidance
Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 51 psi
- Burst Pressure (psi)
- 60 psi
- Capsule Format
- AcroPak 1000
- Compliance Standards
- USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Polypropylene
- Filling Bell (Yes/ No)
- Yes
- Filtration Area
- 1000 cm²
- Flow Rate
- 1.1 L/min at 0.1 bar
- Inlet Connection
- 1/4 to 1/2 in. stepped hose barb
- Length
- 19.3 cm
- Material
- PES
- Max Batch Volume
- 100 L
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 60 °C
- Membrane Brand
- Supor
- Outlet Connection
- 1/4 to 1/2 in. stepped hose barb with filling bell
- Pack Count
- 1
- Pore Size (µm)
- 0.2
- Pre-filter Pore Size
- 0.2
- Prefilter (Yes/No)
- Yes
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- Yes
- Wettability
- Hydrophilic
- Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
- Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.
- Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
- Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
- Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
- Validation Support - Manufacturer documentation including extractable profiles and bacterial challenge data supports regulated process integration.