AcroPak 500 Capsules w/ Supor Membrane - 0.1/0.1um, Gamma-Irradiated , 1/Pk SKU: 12997

Supor (PES) Capsule Filters - 12997

Supor PES capsule filters provide consistent membrane performance from laboratory evaluation through pilot and full production batch volumes within a single validated platform. Moreover, the Supor PES membrane's asymmetric pore architecture delivers industry-leading flow rates and throughput capacity in a validated sterilizing-grade format backed by comprehensive pharmaceutical documentation packages. The outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.

Key Supor (PES) Membrane Characteristics

• Supor PES capsules are backed by comprehensive validation documentation including extractable profiles and bacterial challenge test data from the manufacturer.
• Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
• The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
• Non-sterile configuration accommodates laboratory and industrial applications where the capsule filter serves a clarification or protection function rather than a sterilizing-grade barrier role.
• Supor capsule devices are constructed from materials with documented biocompatibility and low extractable characteristics suitable for pharmaceutical manufacturing processes.

Key Capsule Construction Features

• Hose barb connections enable direct integration with flexible tubing systems commonly used in laboratory and pilot-scale filtration setups.
• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.

Whether your process requires sterilizing-grade retention for a 500-milliliter bench trial or clarification capacity for a 100-liter production batch, the right capsule filter configuration eliminates the compromises between throughput, retention, and operational simplicity. With these demands in mind, if your pharmaceutical process requires validated filtration performance with comprehensive regulatory documentation, Supor PES capsule filters provide the performance data and quality certifications your filing depends on. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

Sterilization Guidance

Supplied non-sterile, the polypropylene housing supports autoclave sterilization at 121 degrees Celsius for 20 minutes when aseptic filtration is required by the application protocol.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

35 psi

Burst Pressure (psi)

60 psi

Capsule Format

AcroPak 500

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Filling Bell (Yes/ No)

Yes

Filtration Area

500 cm²

Flow Rate

0.2 L/min at 0.1 bar

Inlet Connection

1/4 to 1/2 in. stepped hose barb

Length

14.5 cm

Material

PES

Max Batch Volume

50 L

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

60 °C

Membrane Brand

Supor

Outlet Connection

1/4 to 1/2 in. stepped hose barb with filling bell

Pack Count

1

Pore Size (µm)

0.1

Pre-filter Pore Size

0.1

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
• Validation Support - Manufacturer documentation including extractable profiles and bacterial challenge data supports regulated process integration.
• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.