AcroPak 1000 Capsules w/ Supor Membrane - 0.1/0.1um, Gamma-Irradiated , 1/Pk SKU: 12999

Supor (PES) Capsule Filters - 12999

The asymmetric pore structure of Supor PES membranes captures contaminants at the surface while maintaining open channels beneath, delivering high flow rates and dirt-holding capacity. The Supor PES membrane platform scales consistently from laboratory evaluation through production implementation, with capsule effective filtration areas ranging from bench-scale to large-batch formats. The result is a streamlined filtration step that integrates directly into fluid transfer systems, reducing hold times and minimizing the manual handling that compromises sterility assurance.

Key Supor (PES) Membrane Characteristics

• Supor capsule devices are constructed from materials with documented biocompatibility and low extractable characteristics suitable for pharmaceutical manufacturing processes.
• Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
• The Supor membrane platform provides consistent filtration performance across capsule formats from laboratory-scale evaluation devices through production-scale large-volume capsules.
• Rated for operating pressures up to 60 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.
• Maximum operating temperature of 60 degrees Celsius supports filtration of warm solutions and accommodates the thermal conditions present in process environments.

Key Capsule Construction Features

• Hose barb connections enable direct integration with flexible tubing systems commonly used in laboratory and pilot-scale filtration setups.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.

When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. For biopharmaceutical manufacturing where retention validation and product recovery are equally critical, Supor membrane technology delivers the documented performance and ultra-low binding your process demands. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

Sterilization Guidance

Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

35 psi

Burst Pressure (psi)

60 psi

Capsule Format

AcroPak 1000

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Polypropylene

Filling Bell (Yes/ No)

Yes

Filtration Area

1000 cm²

Flow Rate

0.4 L/min at 0.1 bar

Inlet Connection

1/4 to 1/2 in. stepped hose barb

Length

19.3 cm

Material

PES

Max Batch Volume

100 L

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

60 °C

Membrane Brand

Supor

Outlet Connection

1/4 to 1/2 in. stepped hose barb with filling bell

Pack Count

1

Pore Size (µm)

0.1

Pre-filter Pore Size

0.1

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

Yes

Wettability

Hydrophilic

• Validation Support - Manufacturer documentation including extractable profiles and bacterial challenge data supports regulated process integration.
• Cell Culture Media - High-throughput filtration of tissue culture media with flow rates optimized for large-volume batch processing.
• Process Compatibility - Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14.
• Buffer Systems - Broad pH compatibility from 1 to 14 supports validated filtration across the full range of pharmaceutical buffer solutions.
• Biologics Processing - Ultra-low binding PES membrane preserves therapeutic protein concentrations through production-scale processing.
• Scale-Up Filtration - Consistent Supor membrane performance from laboratory evaluation through pilot and full production batch volumes.