Acro Disc Syringe Filters w/ PVDF Membrane - 0.2um, 25mm, 200/Pk
Pall SKU: 4406

Pall Acrodisc PVDF Syringe Filters, 0.2 µm, 25 mm, 200/Pk - 4406

Pall Corporation brings decades of fluid management expertise to laboratory-scale filtration challenges. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. PVDF resists HPLC mobile phases, alcohols, and mild hydrocarbons and draws aqueous mobile phases through without pre-wetting. The polypropylene housing holds a reliable seal against the membrane edge while routing flow to minimize backpressure in service and stays inert across common laboratory solvents. Where analytical results depend on clean samples, syringe filtration removes particulates at the moment of preparation.

Technical Specifications

• Absolute pore size rating gives consistent results across protocols
• Low extractables preserve a clean chromatographic baseline
• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Thin membrane structure sustains high flow for fast sample throughput

Housing Specifications

• Resists stress cracking from aqueous salt and buffer solutions
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Stable across the full aqueous pH range in routine sample work
• Rigid polypropylene body holds its shape under manual filtration pressure

Filtering every buffer before loading keeps your instrument running clean and uninterrupted. Upstream buffer clarification keeps avoidable particulates out of your flow path before they reach the column inlet or detector. Review our Chemical Compatibility Chart, or ask technical service to confirm chemical compatibility for your specific application.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

39psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

50ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

200

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection