Acro Disc Syringe Filters w/ PVDF Membrane - 0.45um, 25mm, 200/Pk
Pall SKU: 4408

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 25 mm, 200/Pk - 4408

Quality controls spanning raw membrane casting through final device integrity testing ensure consistent performance across Pall production lots. A syringe filter seats a membrane in a sealed housing that threads onto a standard luer fitting. PVDF holds up to alcohols and mild hydrocarbon solvents while wetting aqueous and HPLC samples on contact and preserves dilute proteins and analytes in the filtrate. Polypropylene construction maintains a low-dead-volume internal flow path while resisting aqueous acids, bases, and alcohols in routine use and maintains housing integrity through the filtration run. When sterile or particle-free preparation matters at the bench, the syringe filter delivers it with minimal added handling.

Technical Specifications

• Mechanically durable membrane holds integrity under filtration pressure
• Absolute pore size rating gives consistent results across protocols
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Low extractables preserve a clean chromatographic baseline
• Resists HPLC mobile phases, alcohols, and mild hydrocarbons

Housing Specifications

• Tough polypropylene body tolerates repeated handling at the bench
• Plasticizer-free polyolefin construction keeps the fluid path clean
• Stable across the full aqueous pH range in routine sample work
• Rigid polypropylene body holds its shape under manual filtration pressure

A clean particulate separation keeps your aqueous sample preparation dependable. General-purpose aqueous filtration supports the sample types you handle every day across your water-analysis and general analytical workflows. Reach out to the Tisch Scientific team for application support, volume pricing, and technical assistance with your filtration product selection.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection