Pall
Acro Disc 25mm, 0.45um, PVDF, 50/Pk SKU: 4408TC

Polyvinylidene Difluoride (PVDF) Syringe Filters, 0.45µm, 25mm - 4408TC

Designed to protect sensitive chromatography columns from clogging, the Polyvinylidene Difluoride (PVDF) Syringe Filters delivers exceptional retention of particulates without compromising flow rates. To ensure analytical precision, the unit is constructed with a high-grade Polyvinylidene Difluoride (PVDF) membrane providing a consistent 0.45 cutoff that passes only your target analyte. Designed to facilitate rapid processing, the housing features an optimized flow geometry that minimizes backpressure, allowing for easier manual filtration even with viscous samples. Consequently, by reducing the risk of downstream contamination, these filters serve as a critical safeguard for the integrity of your experimental results.

Key Polyvinylidene Difluoride (PVDF) Membrane Characteristics

• Polyvinylidene Difluoride (PVDF) membrane with hydrophilic (hplc) / hydrophobic (venting) affinity
• Ultra-Low Protein Binding characteristics
• Excellent resistance to HPLC mobile phases, alcohols, and mild hydrocarbons
• Incompatible with acetone, DMSO, or strong bases (> pH 12)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 2.8cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

When you integrate these filters into your daily standard operating procedures, you are choosing a workflow that prioritizes efficiency without compromising results. You invest significant resources into your samples; safeguarding them with a proven filtration barrier is a cost-effective insurance policy for your lab. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Connection Type

Luer-Lock/ Luer Slip

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

50

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophobic

• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation