Pall
Acro Disc Syringe Filters w/ Nylon Membrane - 0.45um, 25mm, 200/Pk SKU: 4438

Nylon (NY) Syringe Filters, 0.45µm, 25mm - 4438

For researchers requiring consistent baselines in HPLC and dissolution testing, the Nylon Syringe Filters offers a robust solution for extending instrument life. At the core of the device is a uniform Nylon matrix, delivering high dirt-loading capacity and reliable exclusion of interfering particles. Encasing this critical media is a high-purity polypropylene housing that prevents sample bypass and ensures that every microliter is processed with high fidelity. The result is a filtration solution manufactured in an ISO-certified facility that minimizes distinct interference, providing clean baselines for publication-quality data.

Key Nylon Membrane Characteristics

• Nylon membrane with hydrophilic affinity
• High Protein Binding characteristics
• Excellent resistance to esters, bases, and alcohols
• Avoid with strong acids (pH < 3) or protein samples (high binding)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 3.9cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

By selecting a filter that matches the exact chemical nature of your samples, you ensure that your workflow remains uninterrupted by membrane failures. Protecting your downstream processes requires a defensive strategy, and utilizing these verified filters gives you the peace of mind that your work is safe. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

150ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wetability

Hydrophilic

• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis