Pall
Acro Disc Syringe Filters w/ PVDF Membrane - 0.45um, 13mm, Minispike Outlet, 300/Pk SKU: 4452

Polyvinylidene Difluoride (PVDF) Syringe Filters, 0.45µm, 13mm - 4452

For researchers requiring consistent baselines in HPLC and dissolution testing, the Polyvinylidene Difluoride (PVDF) Syringe Filters offers a robust solution for extending instrument life. To ensure analytical precision, the unit is constructed with a high-grade Polyvinylidene Difluoride (PVDF) membrane providing a consistent 0.45 cutoff that passes only your target analyte. To guarantee structural reliability, each unit undergoes strict quality control to ensure the housing and membrane seal withstand standard operating pressures without leakage. The result is a filtration solution manufactured in an ISO-certified facility that minimizes distinct interference, providing clean baselines for publication-quality data.

Key Polyvinylidene Difluoride (PVDF) Membrane Characteristics

• Polyvinylidene Difluoride (PVDF) membrane with hydrophilic (hplc) / hydrophobic (venting) affinity
• Ultra-Low Protein Binding characteristics
• Excellent resistance to HPLC mobile phases, alcohols, and mild hydrocarbons
• Incompatible with acetone, DMSO, or strong bases (> pH 12)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Minispike for secure fitting
• 1.0cm² effective filtration area
• < 30 µl holdup volume to minimize sample loss

By selecting a filter that matches the exact chemical nature of your samples, you ensure that your workflow remains uninterrupted by membrane failures. Trust in the consistent performance of your filtration step to remove the variables that often lead to costly re-runs and ambiguous data. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

50psi

Connection Type

Luer-Lock/ Minispike

Construction

Polypropylene (PP)

Diameter

13mm

Filtration Area

1.0cm²

Holdup Volume

< 30 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

100psi

Maximum Operating Temperature (°C)

55°C

Pack Count

300

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophobic

• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection