Acro Disc Syringe Filters w/ PVDF Membrane - 0.45um, 13mm, Minispike Outlet, 300/Pk
Pall SKU: 4452

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 13 mm, 300/Pk - 4452

Pall Corporation brings decades of fluid management expertise to laboratory-scale filtration challenges. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. Hydrophilic PVDF wets aqueous and HPLC samples on contact while holding consistent absolute retention at the rated pore size and holds up to alcohols and mild hydrocarbon solvents. The polypropylene housing holds a reliable seal against the membrane edge and sustains efficient flow on viscous samples. Where analytical results depend on clean samples, syringe filtration removes particulates at the moment of preparation.

Technical Specifications

• Thin membrane structure sustains high flow for fast sample throughput
• Mechanically durable membrane holds integrity under filtration pressure
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Resists HPLC mobile phases, alcohols, and mild hydrocarbons

Housing Specifications

• Rigid polypropylene body holds its shape under manual filtration pressure
• Stable across the full aqueous pH range in routine sample work
• Thermal-bonded construction keeps adhesives out of the fluid path
• Low extractable contribution protects sensitive downstream analyses

A clean particulate separation keeps your aqueous sample preparation dependable. Consistent aqueous clarification keeps your sample preparation moving as a dependable step in your aqueous sample prep. Send your application details to our technical service team and request a filtration product recommendation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

50psi

Connection Type

Luer-Lock/ Minispike

Construction

Polypropylene (PP)

Diameter

13mm

Filtration Area

1.0cm²

Holdup Volume

< 30 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

100psi

Maximum Operating Temperature (°C)

55°C

Pack Count

300

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection