AcroCap Positive Pressure Devices - 0.2um, Gamma-Irradiated , 10/Pk SKU: 4480

Polyethersulfone (PES) Capsule Filters - 4480

When laboratory protocols require more filtration capacity than a syringe filter but less than a full in-line capsule, AcroCap devices fill that operational gap. Built for consistent results, luer lock inlet and luer slip outlet connections provide direct syringe compatibility, enabling positive-pressure filtration through PES membrane media without the tubing infrastructure of larger capsule formats. The outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.

Key Polyethersulfone (PES) Membrane Characteristics

• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
• Single-layer membrane construction provides direct, absolute retention at the rated pore size without the additional flow resistance introduced by upstream prefilter layers.
• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• Rated for operating pressures up to 30 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.

Key Capsule Construction Features

• The translucent acrylic housing enables operators to confirm complete membrane wetting and monitor filtrate flow without interrupting the filtration process.
• Modified acrylic housing delivers low extractable levels suitable for aqueous biological and pharmaceutical filtration applications where fluid purity is a primary concern.
• Lightweight acrylic construction reduces the physical handling demands of capsule installation, particularly in vacuum filtration setups where the device is suspended above the collection vessel.
• Acrylic capsule housing is compatible with gamma irradiation sterilization, arriving factory-sterilized and ready for immediate use in aseptic filtration workflows.

When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. In response, when your application sits between syringe filter and full capsule scale, AcroCap positive-pressure devices bridge that gap with the PES membrane performance your bench-scale work requires. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Housing material limitations preclude autoclave sterilization, making the device appropriate for non-sterile applications including particulate removal, sample clarification, and general-purpose laboratory filtration.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Burst Pressure (psi)

30 psi

Capsule Format

AcroCap

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Modified acrylic

Filling Bell (Yes/ No)

No

Filtration Area

15 cm²

Flow Rate

0.22 L/min at 1 bar

Inlet Connection

Female luer lock

Material

PES

Max Batch Volume

3 L

Maximum Operating Pressure

30 psi

Maximum Operating Temperature (°C)

55 °C

Membrane Brand

Supor

Outlet Connection

Male luer slip

Pack Count

10

Pore Size (µm)

0.2

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Do not re-sterilize

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Bench Filtration - Compact luer-connected membrane filtration for bench-scale sample preparation, reagent clarification, and buffer processing tasks.
• Sample Preparation - Positive-pressure processing of laboratory samples through PES membrane media in a compact, syringe-compatible capsule format.
• Reagent Clarification - Luer-compatible filtration of small reagent volumes where syringe filter throughput is insufficient and in-line capsule setup is excessive.
• Clinical Samples - Small-volume bench filtration of clinical and diagnostic specimens where luer connectivity integrates with existing laboratory fluid handling equipment.
• Method Development - Small-volume filtration during analytical method development where membrane retention must be evaluated before scaling to production capsules.
• Small Volume Processing - Positive-pressure filtration of laboratory solutions in volumes exceeding syringe filter capacity but below in-line capsule scale.