AcroCap Positive Pressure Devices - 0.45um, Gamma-Irradiated , 10/Pk SKU: 4482

Polyethersulfone (PES) Capsule Filters - 4482

For small-volume filtration tasks that exceed syringe filter throughput, AcroCap devices provide PES membrane performance in a compact, luer-compatible format. Engineered for demanding applications, gamma-sterilized acrylic housing arrives ready for use in bench-scale filtration, combining the convenience of a sealed single-use device with the familiar luer interface used across laboratory fluid handling. To this end, the outcome is higher operational throughput with lower contamination risk, as disposable capsule devices remove the reprocessing steps that introduce variability into reusable filter systems.

Key Polyethersulfone (PES) Membrane Characteristics

• Maximum operating pressure of 30 psi provides the differential pressure capacity needed for sustained filtration of viscous solutions and high-flow process streams.
• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
• Single-membrane capsule design provides a straightforward retention barrier for applications where feed quality is controlled and extended dirt-holding capacity is not the primary requirement.
• Non-sterile configuration accommodates laboratory and industrial applications where the capsule filter serves a clarification or protection function rather than a sterilizing-grade barrier role.
• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.

Key Capsule Construction Features

• Acrylic capsule housing is compatible with gamma irradiation sterilization, arriving factory-sterilized and ready for immediate use in aseptic filtration workflows.
• Luer-compatible inlet and outlet connections enable direct attachment to syringes, small-bore tubing, and laboratory fluid handling accessories.
• Sealed acrylic capsule construction is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device ships.
• Modified acrylic housing provides optical clarity for visual monitoring of fluid flow, wetting progress, and air displacement during capsule filtration operations.

As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. For exactly this reason, for small-volume filtration tasks where syringe filter throughput falls short, AcroCap devices provide the additional membrane capacity your sample volumes demand in a compact luer-compatible format. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

Sterilization Guidance

Non-sterile delivery and non-autoclavable housing construction position the device for applications where particle removal and sample clarity are the primary objectives rather than sterile effluent production.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Burst Pressure (psi)

30 psi

Capsule Format

AcroCap

Compliance Standards

USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)

Construction

Modified acrylic

Filling Bell (Yes/ No)

No

Filtration Area

15 cm²

Flow Rate

0.5 L/min at 1 bar

Inlet Connection

Female luer lock

Material

PES

Max Batch Volume

3 L

Maximum Operating Pressure

30 psi

Maximum Operating Temperature (°C)

55 °C

Membrane Brand

Supor

Outlet Connection

Male luer slip

Pack Count

10

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Do not re-sterilize

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Method Development - Small-volume filtration during analytical method development where membrane retention must be evaluated before scaling to production capsules.
• Small Volume Processing - Positive-pressure filtration of laboratory solutions in volumes exceeding syringe filter capacity but below in-line capsule scale.
• Bench Filtration - Compact luer-connected membrane filtration for bench-scale sample preparation, reagent clarification, and buffer processing tasks.
• Reagent Clarification - Luer-compatible filtration of small reagent volumes where syringe filter throughput is insufficient and in-line capsule setup is excessive.
• Sample Preparation - Positive-pressure processing of laboratory samples through PES membrane media in a compact, syringe-compatible capsule format.
• Clinical Samples - Small-volume bench filtration of clinical and diagnostic specimens where luer connectivity integrates with existing laboratory fluid handling equipment.