Pall
Acro Disc Syringe Filters w/ PVDF Membrane - 0.45um, 25mm, 1000/Pk SKU: 4500

Polyvinylidene Difluoride (PVDF) Syringe Filters, 0.45µm, 25mm - 4500

Reducing background noise in analytical assays begins with proper clarification, and the Polyvinylidene Difluoride (PVDF) Syringe Filters is engineered to remove interfering solids efficiently. Facilitating rapid sample turnover, the hydrophilic Polyvinylidene Difluoride (PVDF) membrane structure ensures the 0.45 rating remains consistent even under pressure. Encasing this critical media is a high-purity polypropylene housing that prevents sample bypass and ensures that every microliter is processed with high fidelity. Meeting the needs of regulated environments, this series supports compliance with stringent purity protocols across pharmaceutical and environmental applications.

Key Polyvinylidene Difluoride (PVDF) Membrane Characteristics

• Polyvinylidene Difluoride (PVDF) membrane with hydrophilic (hplc) / hydrophobic (venting) affinity
• Ultra-Low Protein Binding characteristics
• Excellent resistance to HPLC mobile phases, alcohols, and mild hydrocarbons
• Incompatible with acetone, DMSO, or strong bases (> pH 12)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 3.9cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

When you integrate these filters into your daily standard operating procedures, you are choosing a workflow that prioritizes efficiency without compromising results. You invest significant resources into your samples; safeguarding them with a proven filtration barrier is a cost-effective insurance policy for your lab. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophobic

• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications