Acro Disc Syringe Filters w/ PVDF Membrane - 0.45um, 25mm, 1000/Pk
Pall SKU: 4500

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 4500

Pall Corporation brings decades of fluid management expertise to laboratory-scale filtration challenges. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. Hydrophilic PVDF minimizes protein binding for high HPLC sample recovery while holding consistent absolute retention at the rated pore size and wets aqueous and HPLC samples on contact. The PP housing sustains efficient flow on viscous samples while resisting aqueous acids, bases, and alcohols in routine use and holds extractables low for sensitive analyses. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Thin membrane structure sustains high flow for fast sample throughput
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Low extractables preserve a clean chromatographic baseline
• Resists HPLC mobile phases, alcohols, and mild hydrocarbons
• Mechanically durable membrane holds integrity under filtration pressure

Housing Specifications

• Thermal-bonded construction keeps adhesives out of the fluid path
• Low extractable contribution protects sensitive downstream analyses
• Resists stress cracking from aqueous salt and buffer solutions
• Reliable housing-to-membrane seal prevents bypass at rated pressure

A clean particulate separation keeps your aqueous sample preparation dependable. Consistent aqueous clarification keeps your sample preparation moving as a dependable step in your aqueous sample prep. Ask our friendly customer service team to confirm the pore size, membrane, and sterility options your filtration application calls for.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications