Acro Disc Syringe Filters w/ PTFE Membrane - 0.45um, 25mm, 1000/Pk
Pall SKU: 4501

Pall Acrodisc PTFE Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 4501

Pall applies its proprietary membrane manufacturing capabilities, integrating specialized media into the Acrodisc housing geometry. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. PTFE holds consistent absolute retention at the rated pore size and withstands aggressive organics that degrade other media. The PP housing keeps the fluid path low in extractable contamination while holding a reliable seal against the membrane edge and sustains efficient flow on viscous samples. When sterile or particle-free preparation matters at the bench, the syringe filter delivers it with minimal added handling.

Technical Specifications

• Chemically inert against aggressive solvents, strong acids, and alkalis
• Absolute pore size rating gives consistent results across protocols
• Low extractables keep the chromatographic background clean
• Hydrophobic membrane repels water for gas, vent, and solvent filtration
• Stable across a wide operating temperature range for demanding methods

Housing Specifications

• Stable across the full aqueous pH range in routine sample work
• Plasticizer-free polyolefin construction keeps the fluid path clean
• Resists stress cracking from aqueous salt and buffer solutions
• Reliable housing-to-membrane seal prevents bypass at rated pressure

Filtering aggressive solvents and reagents through a filter that holds up to the chemistry keeps your sample prep reliable. Solvent-stream filtration handles the solvents and reagents your methods rely on so your filter holds its integrity through the run. Contact Tisch Scientific for technical guidance on selecting the right filtration product for your specific application requirements.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

9psi (IPA)

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

130ml

Holdup Volume

< 125 µL

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

100°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Pump Protection - Acts as a reliable hydrophobic barrier to protect vacuum pumps from corrosive moisture damage and particulate contamination
• Gas Filtration - Ensures sterility in air and gas lines for fermentation tanks, preventing the introduction of airborne contaminants
• Chemical Synthesis - Resists aggressive organic solvents and corrosive acids, ensuring compatibility with the harshest synthetic reaction mixtures
• Cryogenic Fluids - Delivers consistent performance in extreme temperature environments, filtering cryogenic liquids with exceptional reliability
• Air Monitoring - Ensures precise capture of airborne particulates for environmental analysis in challenging atmospheric monitoring conditions
• Moisture Barrier - Protects sensitive electronic sensors and instruments from aqueous aerosols while allowing gases to pass freely