Acro Disc Syringe Filters w/ Nylon Membrane - 0.45um, 25mm, 1000/Pk
Pall SKU: 4502

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 4502

Pall applies its proprietary membrane manufacturing capabilities, integrating specialized media into the Acrodisc housing geometry. Sample preparation for chromatography often ends with a syringe filter on the path to the vial. The nylon membrane draws aqueous buffers through without pre-wetting while resisting alkaline buffer systems and delivers sharp particle cutoff at the rated pore size. The polypropylene housing holds a reliable seal against the membrane edge and stays inert across common laboratory solvents. For routine sample preparation across many methods, the syringe filter folds clarification into one disposable step.

Technical Specifications

• Stable across the pH 3 to 12 operating range
• High tensile strength for stability under elevated differential pressures
• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• Non-sterile for routine clarification and sample prep
• Alkaline-resistant across a broad range of aqueous buffers

Housing Specifications

• Stable across the full aqueous pH range in routine sample work
• Medical-grade polypropylene with broad chemical compatibility
• Thermal-bonded construction keeps adhesives out of the fluid path
• Optimized internal geometry minimizes backpressure in service

A clean particulate separation keeps your aqueous sample preparation dependable. General-purpose aqueous filtration supports the sample types you handle every day from reagent and buffer preparation through routine sample clarification. Call on the Tisch Scientific team to standardize filtration products across your methods with volume pricing and documentation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

150ml

Holdup Volume

< 125 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients