Pall
Acro Disc Syringe Filters w/ Supor Membrane - 0.45um, 25mm Modified Acrylic Housing, 1000/Pk SKU: 4508

Polyethersulfone (PES) Syringe Filters, 0.45µm, 25mm - 4508

Designed for the biopharmaceutical sector, Supor® technology ensures sterility while minimizing the time your sensitive samples spend in filtration. Driving this biological efficiency is an ultra-low protein binding surface that minimizes the loss of active ingredients during sterile filtration. To guarantee structural reliability, each unit undergoes strict quality control to ensure the housing and membrane seal withstand standard operating pressures without leakage. The result is a filtration solution manufactured in an ISO-certified facility that minimizes distinct interference, providing clean baselines for publication-quality data.

Key Polyethersulfone (PES) Membrane Characteristics

• Polyethersulfone (PES) membrane with hydrophilic affinity
• Ultra-Low Protein Binding characteristics
• Broad compatibility (pH 1-14), ideal for biologicals
• Not compatible with aggressive ketones or esters
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 2.8cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

When you integrate these filters into your daily standard operating procedures, you are choosing a workflow that prioritizes efficiency without compromising results. Protecting your downstream processes requires a defensive strategy, and utilizing these verified filters gives you the peace of mind that your work is safe. Choose Pall technology to ensure that your critical samples are processed with the highest level of recovery and sterility available.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Burst Pressure (psi)

75psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

300ml

Holdup Volume

< 100 µL

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophilic

• Biologicals - Maximizes recovery of high-value proteins and therapeutics during sterile filtration steps, protecting yield in production runs
• Buffer Filtration - Ensures particulate-free buffers for critical downstream processes and instrumentation to prevent costly system downtime
• Time-Sensitive Prep - Accelerates filtration workflows where speed is critical to preserving sample integrity and preventing biological degradation
• Viscous Biologicals - Maintains flow rates even when filtering protein-rich or slightly viscous biological fluids that would clog other filters
• High-Throughput Sterile Filtration - Processes large volumes of biological fluids significantly faster than standard PES to reduce processing time
• Media Preparation - Sterilizes tissue culture media with minimal protein loss, ensuring optimal cell growth and viability in sensitive cultures