Acro Disc Syringe Filters w/ PVDF Membrane - 0.2um, 25mm, 1000/Pk
Pall SKU: 4520

Pall Acrodisc PVDF Syringe Filters, 0.2 µm, 25 mm, 1000/Pk - 4520

Pall Corporation brings decades of fluid management expertise to laboratory-scale filtration challenges. A syringe filter seats a membrane in a sealed housing that threads onto a standard luer fitting. The hydrophilic PVDF membrane draws aqueous mobile phases through without pre-wetting while resisting HPLC mobile phases, alcohols, and mild hydrocarbons and keeps analyte adsorption low for clean recovery. The PP housing keeps the fluid path low in extractable contamination while holding a reliable seal against the membrane edge and maintains a low-dead-volume internal flow path. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Resists HPLC mobile phases, alcohols, and mild hydrocarbons
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Low extractables preserve a clean chromatographic baseline
• Absolute pore size rating gives consistent results across protocols
• Mechanically durable membrane holds integrity under filtration pressure

Housing Specifications

• Medical-grade polypropylene with broad chemical compatibility
• Low extractable contribution protects sensitive downstream analyses
• Rigid polypropylene body holds its shape under manual filtration pressure
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate

Reproducible separations start with samples that reach the column free of particulates. Upstream sample clarification keeps your separations clean and reproducible from sample preparation through final injection. Ask our friendly customer service team to confirm the pore size, membrane, and sterility options your filtration application calls for.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

39psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

50ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

1000

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays