Pall
Acro Disc Syringe Filters w/ PVDF Membrane - 0.2um, 25mm, 1000/Pk SKU: 4520

Polyvinylidene Difluoride (PVDF) Syringe Filters, 0.2µm, 25mm - 4520

For critical applications requiring absolute sterility assurance, the Polyvinylidene Difluoride (PVDF) Syringe Filters series provides a verified barrier against bacterial contamination. Leveraging the specific retention properties of Polyvinylidene Difluoride (PVDF), this device offers a validated 0.2 barrier against microbial contaminants. Complementing the membrane's purity, the housing's thermal bonding eliminates the need for adhesives, removing a common source of extractable contamination. Ultimately, this rigorous attention to manufacturing quality ensures batch-to-batch reproducibility, allowing laboratories to standardize their workflows with total confidence.

Key Polyvinylidene Difluoride (PVDF) Membrane Characteristics

• Polyvinylidene Difluoride (PVDF) membrane with hydrophilic (hplc) / hydrophobic (venting) affinity
• Ultra-Low Protein Binding characteristics
• Excellent resistance to HPLC mobile phases, alcohols, and mild hydrocarbons
• Incompatible with acetone, DMSO, or strong bases (> pH 12)
• 0.2 rating suitable for sterile filtration

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 3.9cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

Your laboratory throughput depends on reliable consumables, and these filters are designed to keep your sequences running smoothly, sample after sample. Protecting your downstream processes requires a defensive strategy, and utilizing these verified filters gives you the peace of mind that your work is safe. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

39psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

50ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

1000

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophobic

• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays