Acro Disc Syringe Filters w/ Nylon Membrane - 0.2um, 25mm, 1000/Pk
Pall SKU: 4522

Pall Acrodisc Nylon Syringe Filters, 0.2 µm, 25 mm, 1000/Pk - 4522

Pall applies its proprietary membrane manufacturing capabilities, integrating specialized media into the Acrodisc housing geometry. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. The nylon membrane comes in a non-sterile format for routine analytical preparation while holding dimensional stability under rated backpressure and holds sterile-rated retention across the operating envelope. The PP housing stays inert across common laboratory solvents and buffers in routine use while holding a reliable seal against the membrane edge and holds extractables low for sensitive analyses. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Absolute pore size rating provides consistent results across filtration protocols
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Stable across the pH 3 to 12 operating range
• Low extractable contribution to sensitive analytical preparations
• Alkaline-resistant across a broad range of aqueous buffers

Housing Specifications

• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Low extractable contribution protects sensitive downstream analyses
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Tough polypropylene body tolerates repeated handling at the bench

Filtering every buffer before loading keeps your instrument running clean and uninterrupted. Reliable particulate removal protects your instruments and your data so column life and baseline stability stay predictable. Reach out to the Tisch Scientific team for application support, volume pricing, and technical assistance with your filtration product selection.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

42psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

75ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols