Acro Disc Syringe Filters w/ Nylon Membrane - GF/0.45um, 25mm, 1000/Pk
Pall SKU: 4528

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 4528

Pall Corporation combines proprietary membrane technology with a housing platform validated for both manual and automated filtration workflows. A syringe filter seats a membrane in a sealed housing that threads onto a standard luer fitting. The nylon membrane holds dimensional stability under rated backpressure while resisting alkaline buffer systems and fits routine analytical sample preparation. The polypropylene housing resists aqueous acids, bases, and alcohols in routine use while keeping the fluid path low in extractable contamination and maintains a low-dead-volume internal flow path. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Stable across the pH 3 to 12 operating range
• Absolute pore size rating provides consistent results across filtration protocols
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• High tensile strength for stability under elevated differential pressures
• Alkaline-resistant across a broad range of aqueous buffers

Housing Specifications

• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Resists stress cracking from aqueous salt and buffer solutions
• Stable across the full aqueous pH range in routine sample work
• Plasticizer-free polyolefin construction keeps the fluid path clean

Filtering buffers, reagents, and aqueous samples keeps your preparation moving and consistent. General-purpose aqueous filtration supports the sample types you handle every day across your water-analysis and general analytical workflows. Ask the Tisch Scientific team about blanket-order pricing and quality documentation for your routine filtration needs.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

150ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Column Protection - Extends the life of analytical columns by reliably removing micro-particulates from hydrophilic mobile phases
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging