Acro Disc Syringe Filters w/ PVDF Membrane - 0.45um, 13mm, Minispike Outlet, 1000/Pk
Pall SKU: 4545

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 13 mm, 1000/Pk - 4545

Pall applies its proprietary membrane manufacturing capabilities, integrating specialized media into the Acrodisc housing geometry. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. PVDF holds up to alcohols and mild hydrocarbon solvents while wetting aqueous and HPLC samples on contact and delivers absolute particle cutoff at the rated pore size. The polypropylene housing holds a reliable seal against the membrane edge while resisting degradation from routine sample matrices and maintains a low-dead-volume internal flow path. Where analytical results depend on clean samples, syringe filtration removes particulates at the moment of preparation.

Technical Specifications

• Mechanically durable membrane holds integrity under filtration pressure
• Low extractables preserve a clean chromatographic baseline
• Thin membrane structure sustains high flow for fast sample throughput
• Absolute pore size rating gives consistent results across protocols
• Ultra-low protein binding preserves dilute analytes for maximum recovery

Housing Specifications

• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Medical-grade polypropylene with broad chemical compatibility
• Resists aqueous acids, bases, and alcohols in routine sample prep

Filtering buffers, reagents, and aqueous samples keeps your preparation moving and consistent. General-purpose aqueous filtration supports the sample types you handle every day from reagent and buffer preparation through routine sample clarification. Start a live chat with our customer support technicians for quick answers to your compatibility, sizing, and sterility questions.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

50psi

Connection Type

Luer-Lock/ Minispike

Construction

Polypropylene (PP)

Diameter

13mm

Filtration Area

1.0cm²

Holdup Volume

< 30 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

100psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns