Acro Disc Syringe Filters w/ Nylon Membrane - GF/0.45um, 25mm, 200/Pk
Pall SKU: 4549

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 25 mm, 200/Pk - 4549

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. Naturally hydrophilic nylon accepts water-based samples without surfactant preconditioning and resists particle shedding through extended cycles. Polypropylene construction resists chemical degradation from routine sample matrices and sustains efficient flow on viscous samples. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Low extractable contribution to sensitive analytical preparations
• Alkaline-resistant across a broad range of aqueous buffers
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• Non-sterile for routine clarification and sample prep

Housing Specifications

• Optimized internal geometry minimizes backpressure in service
• Thermal-bonded construction keeps adhesives out of the fluid path
• Medical-grade polypropylene with broad chemical compatibility
• Resists stress cracking from aqueous salt and buffer solutions

Sample clarification before injection is the cheapest insurance your chromatography system has. Pre-injection filtration protects the resolution your methods depend on by clearing particulates ahead of the column and frits. Reach out to the Tisch Scientific team for application support, volume pricing, and technical assistance with your filtration product selection.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

150ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging