Pall
Acro Disc Syringe Filters w/ Nylon Membrane - GF/0.45um, 25mm, 200/Pk SKU: 4549

Nylon (NY) Syringe Filters, 0.45µm, 25mm - 4549

Reducing background noise in analytical assays begins with proper clarification, and the Nylon Syringe Filters is engineered to remove interfering solids efficiently. Driving this clarification performance is a hydrophilic Nylon membrane featuring a verified 0.45 pore structure that captures target particulates while minimizing holdup volume. To guarantee structural reliability, each unit undergoes strict quality control to ensure the housing and membrane seal withstand standard operating pressures without leakage. Meeting the needs of regulated environments, this series supports compliance with stringent purity protocols across pharmaceutical and environmental applications.

Key Nylon Membrane Characteristics

• Nylon membrane with hydrophilic affinity
• High Protein Binding characteristics
• Excellent resistance to esters, bases, and alcohols
• Avoid with strong acids (pH < 3) or protein samples (high binding)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 3.9cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

Your laboratory throughput depends on reliable consumables, and these filters are designed to keep your sequences running smoothly, sample after sample. You invest significant resources into your samples; safeguarding them with a proven filtration barrier is a cost-effective insurance policy for your lab. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

150ml

Holdup Volume

< 100 µL

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wetability

Hydrophilic

• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging