Acro Disc Syringe Filters w/ Nylon Membrane - 0.45um, 13mm, Minispike Outlet, 300/Pk
Pall SKU: 4551

Pall Acrodisc Nylon Syringe Filters, 0.45 µm, 13 mm, 300/Pk - 4551

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. A syringe filter seats a membrane in a sealed housing that threads onto a standard luer fitting. Nylon stays stable across the pH 3 to 12 buffer range and delivers sharp particle cutoff at the rated pore size. Polypropylene construction maintains a low-dead-volume internal flow path while keeping the fluid path low in extractable contamination and resists degradation from routine sample matrices. Where analytical results depend on clean samples, syringe filtration removes particulates at the moment of preparation.

Technical Specifications

• Low extractable contribution to sensitive analytical preparations
• Absolute pore size rating provides consistent results across filtration protocols
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Stable across the pH 3 to 12 operating range
• High tensile strength for stability under elevated differential pressures

Housing Specifications

• Plasticizer-free polyolefin construction keeps the fluid path clean
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Resists stress cracking from aqueous salt and buffer solutions
• Low extractable contribution protects sensitive downstream analyses

Reproducible separations start with samples that reach the column free of particulates. Pre-injection filtration protects the resolution your methods depend on so your retention times and peak shapes stay consistent. Send your application details to our technical service team and request a filtration product recommendation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

100psi

Connection Type

Luer-Lock/ Minispike

Construction

Polypropylene (PP)

Diameter

13mm

Filtration Area

1.0cm²

Flow Rate

45ml

Holdup Volume

< 30 µL

Material

Nylon

Maximum Operating Pressure

100psi

Maximum Operating Temperature (°C)

55°C

Pack Count

300

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Wettability

Hydrophilic

• Solvent Filtering - Supports the clarification of ester-based solvents with precision, preventing membrane degradation during processing
• HPLC Sample Prep - Clarifies mixed aqueous and organic solvents to ensure stable baselines and protect chromatography columns from clogging
• Chemical Analysis - Withstands aggressive bases and alcohols, making it ideal for tough chemical compatibility filtration challenges in analysis
• Environmental Testing - Provides robust filtration for water quality samples, effectively removing sediments prior to critical analytical testing
• Dissolution Testing - Ensures accurate drug release profiles by reliably filtering samples without interfering with active pharmaceutical ingredients
• Microbiology Prep - Facilitates the effective removal of particulates from culture media, supporting contamination-free cell growth protocols