Acro Disc Syringe Filters w/ Supor Membrane, Sterile - 0.45um, 25mm, 50/Pk
Pall SKU: 4614

Pall Acrodisc Polyethersulfone (PES) Syringe Filters, 0.45 µm, 25 mm, 50/Pk - 4614

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. PES handles strong bases and oils across a broad aqueous range and delivers sharp particle cutoff at the rated pore size. Polypropylene construction holds extractable contribution low for sensitive analyses while preventing sample bypass under rated operating pressure and maintains a low-dead-volume internal flow path. Where analytical results depend on clean samples, syringe filtration removes particulates at the moment of preparation.

Technical Specifications

• Stable across the full pH 1 to 14 operating range
• Low protein binding preserves dilute analytes for maximum recovery
• Absolute pore size rating gives consistent results across protocols
• High flow rate with low extractable background for clean preparations
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications

Housing Specifications

• Resists stress cracking from aqueous salt and buffer solutions
• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Thermal-bonded construction keeps adhesives out of the fluid path
• Optimized internal geometry minimizes backpressure in service

Removing particulates from your buffers and mobile phases extends column life and keeps your baselines steady. Upstream buffer clarification keeps avoidable particulates out of your flow path while keeping the filtrate analytically clean. Connect with our customer support technicians for chemical compatibility guidance and the right filtration product for your workflow.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Burst Pressure (psi)

75psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

300ml

Holdup Volume

< 300 µL

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

50

Pore Size (µm)

0.45

Sterility

Sterile

Wettability

Hydrophilic

• High-Throughput Sterile Filtration - Processes large volumes of biological fluids significantly faster than standard PES to reduce processing time
• Buffer Filtration - Ensures particulate-free buffers for critical downstream processes and instrumentation to prevent costly system downtime
• Media Preparation - Sterilizes tissue culture media with minimal protein loss, ensuring optimal cell growth and viability in sensitive cultures
• Biologicals - Maximizes recovery of high-value proteins and therapeutics during sterile filtration steps, protecting yield in production runs
• Viscous Biologicals - Maintains flow rates even when filtering protein-rich or slightly viscous biological fluids that would clog other filters
• Time-Sensitive Prep - Accelerates filtration workflows where speed is critical to preserving sample integrity and preventing biological degradation