Pall
Acro Disc Syringe Filters w/ Supor Membrane, Sterile - 0.45um, 25mm, 50/Pk SKU: 4614

Polyethersulfone (PES) Syringe Filters, 0.45µm, 25mm - 4614

Supor® polyethersulfone (PES) membranes represent the industry gold standard for high-throughput sterile filtration of biological fluids. Driving this biological efficiency is an ultra-low protein binding surface that minimizes the loss of active ingredients during sterile filtration. Complementing the membrane's purity, the housing's thermal bonding eliminates the need for adhesives, removing a common source of extractable contamination. Meeting the needs of regulated environments, this series supports compliance with stringent purity protocols across pharmaceutical and environmental applications.

Key Polyethersulfone (PES) Membrane Characteristics

• Polyethersulfone (PES) membrane with hydrophilic affinity
• Ultra-Low Protein Binding characteristics
• Broad compatibility (pH 1-14), ideal for biologicals
• Not compatible with aggressive ketones or esters
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 2.8cm² effective filtration area
• < 300 µl holdup volume to minimize sample loss

You can streamline your sample preparation process significantly by adopting a filtration solution designed to handle your specific volume requirements. You can rely on the certified integrity of these units to protect your critical samples and instrumentation from damaging contaminants. Standardize on Pall Acrodisc® filters to guarantee that your laboratory results meet the rigorous demands of modern regulatory standards.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Burst Pressure (psi)

75psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

300ml

Holdup Volume

< 300 µL

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

50

Pore Size (µm)

0.45

Sterility

Sterile

Wetability

Hydrophilic

• High-Throughput Sterile Filtration - Processes large volumes of biological fluids significantly faster than standard PES to reduce processing time
• Buffer Filtration - Ensures particulate-free buffers for critical downstream processes and instrumentation to prevent costly system downtime
• Media Preparation - Sterilizes tissue culture media with minimal protein loss, ensuring optimal cell growth and viability in sensitive cultures
• Biologicals - Maximizes recovery of high-value proteins and therapeutics during sterile filtration steps, protecting yield in production runs
• Viscous Biologicals - Maintains flow rates even when filtering protein-rich or slightly viscous biological fluids that would clog other filters
• Time-Sensitive Prep - Accelerates filtration workflows where speed is critical to preserving sample integrity and preventing biological degradation