VacuCap 0.1um, 90mm, Gamma-Irradiated , 10/Pk SKU: 4621

Polyethersulfone (PES) Capsule Filters - 4621

When bench-scale filtration volumes exceed syringe filter capacity but do not require in-line capsule systems, VacuCap devices bridge the gap with vacuum-driven convenience. On the performance side, bottle-top capsule construction seats the membrane assembly directly above the collection vessel, creating a sealed vacuum-driven fluid path that eliminates the tubing and fittings required by in-line capsule formats. Taken together, the outcome is simplified regulatory documentation and reduced contamination risk, with each single-use capsule providing a validated, traceable filtration event.

Key Polyethersulfone (PES) Membrane Characteristics

• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
• Non-sterile capsule delivery is appropriate for clarification, prefiltration, and general laboratory applications where the filtrate does not require sterility assurance.
• Maximum operating pressure of 25 in. Hg (vacuum) psi provides the differential pressure capacity needed for sustained filtration of viscous solutions and high-flow process streams.
• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.

Key Capsule Construction Features

• Sealed acrylic capsule construction is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device ships.
• Lightweight acrylic construction reduces the physical handling demands of capsule installation, particularly in vacuum filtration setups where the device is suspended above the collection vessel.
• Acrylic capsule housing is compatible with gamma irradiation sterilization, arriving factory-sterilized and ready for immediate use in aseptic filtration workflows.
• Modified acrylic housing provides optical clarity for visual monitoring of fluid flow, wetting progress, and air displacement during capsule filtration operations.

As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. If your laboratory prepares culture media, buffers, or reagents at bench scale, VacuCap bottle-top filtration delivers membrane-grade retention with the vacuum-driven simplicity your daily workflow demands. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Supplied non-sterile, the housing construction does not support autoclave sterilization and is intended for clarification, prefiltration, and general laboratory applications where sterile effluent is not required.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Capsule Format

VacuCap

Compliance Standards

Endotoxin < 0.25 EU/mL (LAL)

Construction

Modified acrylic

Diameter

9 cm

Filling Bell (Yes/ No)

No

Filtration Area

60 cm²

Flow Rate

0.1 L/min at 10 in. Hg

Holdup Volume

4.3 mL

Inlet Connection

Feed tubing port

Material

PES

Max Batch Volume

5 L

Maximum Operating Pressure

25 in. Hg (vacuum)

Maximum Operating Temperature (°C)

55 °C

Membrane Brand

Supor

Outlet Connection

Vacuum port (bottle-top seal)

Pack Count

10

Pore Size (µm)

0.1

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Not suitable for sterile applications

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Reagent Processing - Convenient benchtop filtration of aqueous reagents and solutions where pump infrastructure is unavailable or impractical.
• Small Batch Media - Preparation of filtered tissue culture media in volumes suited to individual experiments and small-scale cell culture operations.
• Laboratory Convenience - Bench-scale vacuum filtration eliminates the tubing and pump setups required by in-line capsule devices.
• Water Polishing - Final filtration of laboratory-grade water into sterile collection vessels for cell culture and sensitive analytical applications.
• Media Preparation - Bench-scale filtration of tissue culture media and biological supplements using vacuum-driven bottle-top convenience.
• Buffer Clarification - Vacuum filtration of laboratory buffers and reagent solutions directly into collection bottles for immediate use.