VacuCap 0.2um, 90mm, Gamma-Irradiated , 10/Pk SKU: 4622

Polyethersulfone (PES) Capsule Filters - 4622

Gamma-sterilized and ready for immediate use, VacuCap capsule filters provide membrane filtration in a bottle-top format designed for bench-scale laboratory convenience and operational simplicity. Transparent acrylic housing allows visual confirmation of membrane wetting, fluid flow, and air displacement during vacuum-driven filtration, providing process feedback without interrupting the operation. In combination, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Polyethersulfone (PES) Membrane Characteristics

• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
• The inherently hydrophilic PES membrane wets immediately on contact with aqueous solutions, eliminating alcohol pre-flush steps and reducing both startup time and solvent waste.
• The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.
• Capsule holdup volume of 4.3 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.
• Ultra-low protein binding characteristics of the PES membrane minimize adsorptive losses, preserving the concentration and biological activity of filtered proteins, antibodies, and growth factors.

Key Capsule Construction Features

• Modified acrylic housing provides optical clarity for visual monitoring of fluid flow, wetting progress, and air displacement during capsule filtration operations.
• Modified acrylic housing delivers low extractable levels suitable for aqueous biological and pharmaceutical filtration applications where fluid purity is a primary concern.
• The translucent acrylic housing enables operators to confirm complete membrane wetting and monitor filtrate flow without interrupting the filtration process.
• Acrylic capsule housing is compatible with gamma irradiation sterilization, arriving factory-sterilized and ready for immediate use in aseptic filtration workflows.

As single-use filtration continues to replace reusable housings across pharmaceutical and laboratory environments, your capsule filter selection determines both the quality of the filtrate and the efficiency of the workflow. With these demands in mind, when your filtration volumes fall between syringe filter capacity and in-line capsule scale, VacuCap bottle-top devices fill that gap with the vacuum-driven simplicity your benchtop applications need. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

Sterilization Guidance

Supplied non-sterile, the housing construction does not support autoclave sterilization and is intended for clarification, prefiltration, and general laboratory applications where sterile effluent is not required.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Capsule Format

VacuCap

Compliance Standards

Endotoxin < 0.25 EU/mL (LAL)

Construction

Modified acrylic

Diameter

9 cm

Filling Bell (Yes/ No)

No

Filtration Area

60 cm²

Flow Rate

0.4 L/min at 10 in. Hg

Holdup Volume

4.3 mL

Inlet Connection

Feed tubing port

Material

PES

Max Batch Volume

5 L

Maximum Operating Pressure

25 in. Hg (vacuum)

Maximum Operating Temperature (°C)

55 °C

Membrane Brand

Supor

Outlet Connection

Vacuum port (bottle-top seal)

Pack Count

10

Pore Size (µm)

0.2

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Not suitable for sterile applications

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Buffer Clarification - Vacuum filtration of laboratory buffers and reagent solutions directly into collection bottles for immediate use.
• Reagent Processing - Convenient benchtop filtration of aqueous reagents and solutions where pump infrastructure is unavailable or impractical.
• Water Polishing - Final filtration of laboratory-grade water into sterile collection vessels for cell culture and sensitive analytical applications.
• Laboratory Convenience - Bench-scale vacuum filtration eliminates the tubing and pump setups required by in-line capsule devices.
• Small Batch Media - Preparation of filtered tissue culture media in volumes suited to individual experiments and small-scale cell culture operations.
• Media Preparation - Bench-scale filtration of tissue culture media and biological supplements using vacuum-driven bottle-top convenience.