VacuCap 0.8/0.2um, 90mm, Gamma-Irradiated , 10/Pk SKU: 4628

Polyethersulfone (PES) Capsule Filters - 4628

Gamma-sterilized and ready for immediate use, VacuCap capsule filters provide membrane filtration in a bottle-top format designed for bench-scale laboratory convenience and operational simplicity. Bottle-top capsule construction seats the membrane assembly directly above the collection vessel, creating a sealed vacuum-driven fluid path that eliminates the tubing and fittings required by in-line capsule formats. In effect, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Polyethersulfone (PES) Membrane Characteristics

• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
• The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• The inherently hydrophilic PES membrane wets immediately on contact with aqueous solutions, eliminating alcohol pre-flush steps and reducing both startup time and solvent waste.
• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.

Key Capsule Construction Features

• The translucent acrylic housing enables operators to confirm complete membrane wetting and monitor filtrate flow without interrupting the filtration process.
• Integrated bottle-top sealing geometry provides a contamination-resistant interface between the capsule and collection vessel during vacuum-assisted filtration operations.
• Sealed acrylic capsule construction is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device ships.
• Modified acrylic housing provides optical clarity for visual monitoring of fluid flow, wetting progress, and air displacement during capsule filtration operations.

As batch volumes and regulatory expectations continue to grow, your capsule filter selection becomes a process design decision that affects sterility assurance, product recovery, and operational cost per liter filtered. In this context, for bench-scale filtration tasks where pump infrastructure and tubing connections add unnecessary complexity, VacuCap devices provide the operational convenience your laboratory routine requires. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

Sterilization Guidance

Supplied non-sterile, the housing construction does not support autoclave sterilization and is intended for clarification, prefiltration, and general laboratory applications where sterile effluent is not required.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Capsule Format

VacuCap

Compliance Standards

Endotoxin < 0.25 EU/mL (LAL)

Construction

Modified acrylic

Diameter

9 cm

Filling Bell (Yes/ No)

No

Filtration Area

60 cm²

Flow Rate

0.4 L/min at 10 in. Hg

Holdup Volume

4.3 mL

Inlet Connection

Feed tubing port

Material

PES

Max Batch Volume

5 L

Maximum Operating Pressure

25 in. Hg (vacuum)

Maximum Operating Temperature (°C)

55 °C

Membrane Brand

Supor

Outlet Connection

Vacuum port (bottle-top seal)

Pack Count

10

Pore Size (µm)

0.2

Pre-filter Pore Size

0.8

Prefilter (Yes/No)

Yes

Sterility

Nonsterile

Sterilization

Not suitable for sterile applications

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Buffer Clarification - Vacuum filtration of laboratory buffers and reagent solutions directly into collection bottles for immediate use.
• Reagent Processing - Convenient benchtop filtration of aqueous reagents and solutions where pump infrastructure is unavailable or impractical.
• Laboratory Convenience - Bench-scale vacuum filtration eliminates the tubing and pump setups required by in-line capsule devices.
• Media Preparation - Bench-scale filtration of tissue culture media and biological supplements using vacuum-driven bottle-top convenience.
• Water Polishing - Final filtration of laboratory-grade water into sterile collection vessels for cell culture and sensitive analytical applications.
• Small Batch Media - Preparation of filtered tissue culture media in volumes suited to individual experiments and small-scale cell culture operations.