VacuCap 0.1um, 60mm, Gamma-Irradiated , 10/Pk SKU: 4631

Polyethersulfone (PES) Capsule Filters - 4631

VacuCap capsule filters eliminate the tubing connections and pump setups associated with traditional capsule filtration, providing a compact vacuum-driven alternative for routine laboratory use. Furthermore, bottle-top capsule construction seats the membrane assembly directly above the collection vessel, creating a sealed vacuum-driven fluid path that eliminates the tubing and fittings required by in-line capsule formats. The outcome is simplified regulatory documentation and reduced contamination risk, with each single-use capsule providing a validated, traceable filtration event.

Key Polyethersulfone (PES) Membrane Characteristics

• The 2.2 milliliter holdup volume reflects the capsule's internal fluid path geometry, relevant to recovery calculations for precious samples and small-batch pharmaceutical formulations.
• The inherently hydrophilic PES membrane wets immediately on contact with aqueous solutions, eliminating alcohol pre-flush steps and reducing both startup time and solvent waste.
• The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.
• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
• Rated for continuous operation at temperatures up to 55 degrees Celsius, the capsule maintains structural integrity and retention performance across the normal process temperature range.

Key Capsule Construction Features

• Lightweight acrylic construction reduces the physical handling demands of capsule installation, particularly in vacuum filtration setups where the device is suspended above the collection vessel.
• The translucent acrylic housing enables operators to confirm complete membrane wetting and monitor filtrate flow without interrupting the filtration process.
• Acrylic capsule housing is compatible with gamma irradiation sterilization, arriving factory-sterilized and ready for immediate use in aseptic filtration workflows.
• Sealed acrylic capsule construction is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device ships.

When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. To support this, for bench-scale filtration tasks where pump infrastructure and tubing connections add unnecessary complexity, VacuCap devices provide the operational convenience your laboratory routine requires. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Supplied non-sterile, the housing construction does not support autoclave sterilization and is intended for clarification, prefiltration, and general laboratory applications where sterile effluent is not required.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Capsule Format

VacuCap

Compliance Standards

Endotoxin < 0.25 EU/mL (LAL)

Construction

Modified acrylic

Diameter

6 cm

Filling Bell (Yes/ No)

No

Filtration Area

30 cm²

Flow Rate

0.05 L/min at 10 in. Hg

Holdup Volume

2.2 mL

Inlet Connection

Feed tubing port

Material

PES

Max Batch Volume

1 L

Maximum Operating Pressure

25 in. Hg (vacuum)

Maximum Operating Temperature (°C)

55 °C

Membrane Brand

Supor

Outlet Connection

Vacuum port (bottle-top seal)

Pack Count

10

Pore Size (µm)

0.1

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Not suitable for sterile applications

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Laboratory Convenience - Bench-scale vacuum filtration eliminates the tubing and pump setups required by in-line capsule devices.
• Small Batch Media - Preparation of filtered tissue culture media in volumes suited to individual experiments and small-scale cell culture operations.
• Water Polishing - Final filtration of laboratory-grade water into sterile collection vessels for cell culture and sensitive analytical applications.
• Buffer Clarification - Vacuum filtration of laboratory buffers and reagent solutions directly into collection bottles for immediate use.
• Reagent Processing - Convenient benchtop filtration of aqueous reagents and solutions where pump infrastructure is unavailable or impractical.
• Media Preparation - Bench-scale filtration of tissue culture media and biological supplements using vacuum-driven bottle-top convenience.