Supor (PES) Capsule Filters - 4632
Gamma-sterilized and ready for immediate use, VacuCap capsule filters provide membrane filtration in a bottle-top format designed for bench-scale laboratory convenience and operational simplicity. PES membrane within the VacuCap housing provides the same retention and low-binding characteristics available in larger in-line capsules, scaled to bench-volume filtration through a compact bottle-top device. To this end, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.
Key Supor (PES) Membrane Characteristics
- The asymmetric Supor membrane structure maximizes dirt-holding capacity and flow rates, delivering throughput performance that reduces the number of capsule devices required per batch.
- Internal holdup volume of 2.2 milliliters minimizes sample loss during capsule filtration, a critical consideration when processing expensive biologics or limited-volume preparations.
- Supor PES membrane technology achieves the lowest protein binding levels in the polyethersulfone category, preserving biologics through the filtration process with minimal adsorptive losses.
- Factory sterilization of the complete capsule assembly ensures that all fluid-contact surfaces meet sterility requirements without relying on user-performed sterilization procedures.
- Supor PES membrane exhibits broad compatibility with aqueous buffers, aliphatic alcohols, and glycols across pH 1-14, supporting diverse pharmaceutical processing applications within a single membrane platform.
Key Capsule Construction Features
- The translucent acrylic housing enables operators to confirm complete membrane wetting and monitor filtrate flow without interrupting the filtration process.
- Bottle-top vacuum filtration design seats directly on standard laboratory collection vessels, creating a sealed fluid path from feed tubing through the membrane to the receiving container.
- Lightweight acrylic construction reduces the physical handling demands of capsule installation, particularly in vacuum filtration setups where the device is suspended above the collection vessel.
- Modified acrylic housing delivers low extractable levels suitable for aqueous biological and pharmaceutical filtration applications where fluid purity is a primary concern.
Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. For this purpose, for bench-scale filtration tasks where pump infrastructure and tubing connections add unnecessary complexity, VacuCap devices provide the operational convenience your laboratory routine requires. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.
Sterilization Guidance
Sealed sterile packaging preserves validated sterility throughout storage and transport, providing a documented sterile barrier that is ready for use at the point of need.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Capsule Format
- VacuCap
- Compliance Standards
- Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Modified acrylic
- Diameter
- 6 cm
- Filling Bell (Yes/ No)
- No
- Filtration Area
- 30 cm²
- Flow Rate
- 0.2 L/min at 10 in. Hg
- Holdup Volume
- 2.2 mL
- Inlet Connection
- Feed tubing port
- Material
- PES
- Max Batch Volume
- 1 L
- Maximum Operating Pressure
- 25 in. Hg (vacuum)
- Maximum Operating Temperature (°C)
- 55 °C
- Membrane Brand
- Supor
- Outlet Connection
- Vacuum port (bottle-top seal)
- Pack Count
- 10
- Pore Size (µm)
- 0.2
- Prefilter (Yes/No)
- No
- Sterility
- Sterile
- Sterilization
- Do not re-sterilize
- Vent (Yes/ No)
- No
- Wettability
- Hydrophilic
- Buffer Clarification - Vacuum filtration of laboratory buffers and reagent solutions directly into collection bottles for immediate use.
- Water Polishing - Final filtration of laboratory-grade water into sterile collection vessels for cell culture and sensitive analytical applications.
- Small Batch Media - Preparation of filtered tissue culture media in volumes suited to individual experiments and small-scale cell culture operations.
- Laboratory Convenience - Bench-scale vacuum filtration eliminates the tubing and pump setups required by in-line capsule devices.
- Media Preparation - Bench-scale filtration of tissue culture media and biological supplements using vacuum-driven bottle-top convenience.
- Reagent Processing - Convenient benchtop filtration of aqueous reagents and solutions where pump infrastructure is unavailable or impractical.