Pall
Acro Disc Syringe Filters w/ Posidyne Membrane Optimized for Scale Up, 25mm - 0.2um , Sterile, 50/Pk SKU: 4908-N

Positively Charged Nylon (Posidyne) (NY+) Syringe Filters, 0.2µm, 25mm - 4908-N

Posidyne® membrane filters leverage a patented charge-modified Nylon 6,6 surface to offer enhanced retention capabilities beyond simple sieving. Driving this enhanced purity is an electrokinetic mechanism that retains endotoxins and fine contaminants smaller than the physical pore rating. Designed to facilitate rapid processing, the housing features an optimized flow geometry that minimizes backpressure, allowing for easier manual filtration even with viscous samples. Ultimately, this rigorous attention to manufacturing quality ensures batch-to-batch reproducibility, allowing laboratories to standardize their workflows with total confidence.

Key Positively Charged Nylon (Posidyne) Membrane Characteristics

• Positively Charged Nylon (Posidyne) membrane with hydrophilic (positively charged) affinity
• High Protein Binding (Electrostatic) characteristics
• Compatible with aqueous solutions and broad pH ranges
• Zeta potential is pH dependent; strictly single-use
• 0.2 rating suitable for sterile filtration

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 2.8cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

Your laboratory throughput depends on reliable consumables, and these filters are designed to keep your sequences running smoothly, sample after sample. You can rely on the certified integrity of these units to protect your critical samples and instrumentation from damaging contaminants. Choose Pall technology to ensure that your critical samples are processed with the highest level of recovery and sterility available.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

46psi

Connection Type

Luer-Lock/ Luer Slip

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

77ml

Holdup Volume

< 100 µL

Material

Positively Charged Nylon (Posidyne)

Maximum Operating Pressure

80psi

Maximum Operating Temperature (°C)

55°C

Pack Count

50

Pore Size (µm)

0.2

Sterility

Sterile

Sterilization

Autoclavable at 121°C for 15–20 min

Wetability

Hydrophilic

• Endotoxin Removal - Electrostatically retains negatively charged endotoxins from aqueous solutions to ensure safety in critical biological apps
• Charged Particle Capture - Selectively removes negatively charged colloids from suspension to clarify complex solutions effectively and reliably
• Water Purification - Bio-reduces water systems by capturing fine contaminants and bacteria to maintain ultrapure water standards in the lab
• Ultrapure Analysis - Provides enhanced retention for critical water quality testing beyond mechanical sieving limits of standard membranes
• Mycoplasma Reduction - Offers additional security against negatively charged biological contaminants to protect valuable cell culture lines
• Pre-filtration - Acts as a charge-based prefilter to protect downstream sterile filters from endotoxin breakthrough and premature fouling