Acro Disc Syringe Filters w/ wwPTFE Membrane - 0.45um, 25mm, 200/Pk
Pall SKU: 4914

Pall Acrodisc PTFE Syringe Filters, 0.45 µm, 25 mm, 200/Pk - 4914

Pall Corporation engineers proprietary membrane media and the Acrodisc housing platform, purpose-built for demanding analytical and bioprocess workflows. Across analytical workflows, the syringe filter is where particulates leave the sample stream. PTFE filters aggressive organic solvents without swelling or breakdown while resisting attack from the harshest process chemistries and holds consistent absolute retention at the rated pore size. The PP housing stays inert across common laboratory solvents and buffers in routine use while maintaining housing integrity through the filtration run and maintains a low-dead-volume internal flow path. Where small-volume samples must reach the instrument clean, syringe filtration clears particulates in a single pass.

Technical Specifications

• Low extractables keep the chromatographic background clean
• Surface-treated for direct aqueous wetting without alcohol pre-wetting
• Stable across a wide operating temperature range for demanding methods
• Absolute pore size rating gives consistent results across protocols
• Filters aggressive organic solvents without swelling or breakdown

Housing Specifications

• Low extractable contribution protects sensitive downstream analyses
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Resists stress cracking from aqueous salt and buffer solutions
• Medical-grade polypropylene with broad chemical compatibility

A clean particulate separation keeps your aqueous sample preparation dependable. Consistent aqueous clarification keeps your sample preparation moving across the buffers and reagents your methods rely on. Start a live chat with our customer support technicians for quick answers to your compatibility, sizing, and sterility questions.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

9psi (IPA)

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

240ml

Holdup Volume

< 100 µL

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Solvent Selection - Eliminates the risk of membrane incompatibility when switching between different solvent systems during method development
• Universal Filtration - Handles both aqueous and organic samples with a single device, reducing inventory complexity and preventing selection errors
• Ion Chromatography - Provides a clean filtrate for sensitive ion analysis, minimizing background interference and ensuring accurate quantification
• UHPLC/HPLC Prep - Certified for low extractables to ensure noise-free baselines in sensitive chromatography applications and trace analysis
• Sample Protection - Low-binding properties ensure maximum recovery of low-concentration analytes to improve the accuracy of quantitative assays
• Dissolution Testing - Simplifies workflows by filtering diverse media types without the need for pre-wetting, streamlining high-volume protocols