Acro Disc Syringe Filters w/ wwPTFE Membrane - 0.45um, 25mm, 1000/Pk
Pall SKU: 4932

Pall Acrodisc PTFE Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 4932

Quality controls spanning raw membrane casting through final device integrity testing ensure consistent performance across Pall production lots. Under hand pressure from the syringe, the membrane captures particulates as the sample passes through. PTFE suits solvent and reagent filtration where other membranes fail while holding consistent absolute retention at the rated pore size and withstands aggressive organics that degrade other media. The polypropylene housing resists aqueous acids, bases, and alcohols in routine use and contributes minimal extractables to the filtrate. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Absolute pore size rating gives consistent results across protocols
• Low extractables keep the chromatographic background clean
• Filters aggressive organic solvents without swelling or breakdown
• Stable across a wide operating temperature range for demanding methods
• Chemically inert against aggressive solvents, strong acids, and alkalis

Housing Specifications

• Resists stress cracking from aqueous salt and buffer solutions
• Optimized internal geometry minimizes backpressure in service
• Stable across the full aqueous pH range in routine sample work
• Resists aqueous acids, bases, and alcohols in routine sample prep

Sample clarification before injection is the cheapest insurance your chromatography system has. Pre-injection filtration protects the resolution your methods depend on across your chromatography methods. Connect with our customer support technicians for chemical compatibility guidance and the right filtration product for your workflow.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

9psi (IPA)

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.8cm²

Flow Rate

130ml

Holdup Volume

< 100 µL

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Universal Filtration - Handles both aqueous and organic samples with a single device, reducing inventory complexity and preventing selection errors
• Sample Protection - Low-binding properties ensure maximum recovery of low-concentration analytes to improve the accuracy of quantitative assays
• UHPLC/HPLC Prep - Certified for low extractables to ensure noise-free baselines in sensitive chromatography applications and trace analysis
• Solvent Selection - Eliminates the risk of membrane incompatibility when switching between different solvent systems during method development
• Ion Chromatography - Provides a clean filtrate for sensitive ion analysis, minimizing background interference and ensuring accurate quantification
• Dissolution Testing - Simplifies workflows by filtering diverse media types without the need for pre-wetting, streamlining high-volume protocols