GLA-5000 PVC Membrane Disc Filters - 5um, 25mm, 100/Pk SKU: 66466

Nylon Membrane Filters - 66466

Designed to deliver reproducibility and confidence across critical sample types, the Pall 66466 provides the filtration consistency that method validation demands. Complementing this, verified 5.0 pore distribution across the Hydrophobic membrane surface guarantees batch-to-batch consistency in particle capture and analyte passage. In effect, controlled production conditions produce membranes with documented pore size distribution and thickness tolerances, supporting method reproducibility across multiple filter lots.

Material Specifications

• High mechanical strength allows Nylon membranes to withstand elevated differential pressures without structural deformation.
• Materials of construction maintain their mechanical and chemical properties at temperatures up to 52°C, supporting heated filtration protocols.
• Alkaline-resistant and compatible with a broad range of aqueous buffers used in pharmaceutical and biotechnology laboratories.
• Broad compatibility with alcohols, aliphatic hydrocarbons, and aromatic solvents extends Nylon filtration into mixed-solvent sample preparation.
• Economical bulk packaging supports laboratories with high consumable throughput where individual sterile wrapping is unnecessary.

Reporting filtration parameters alongside your analytical results demands documented pore size, material chemistry, and lot traceability — the membrane specifications above provide the specificity that reviewers and auditors expect. For applications like these, nylon's compatibility with both aqueous and moderate organic solvent systems lets you standardize on one membrane type across HPLC sample prep workflows that alternate between reversed-phase and normal-phase mobile phases. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1psi

Color

White

Diameter

25mm

Extractables

< 0.5% (Low Ash)

Filtration Area

4.08cm²

Flow Rate

14 LPM (Air)

Grid (Yes/No)

No

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

52°C

Membrane Thickness (µm)

135 – 165µm

Pack Count

100

pH Range

3-14

Pore Size (µm)

5

Sterility

Nonsterile

Sterilization

Non-autoclavable

Support Material

N/A

Wettability

Hydrophobic

• Alkaline Filtration - Withstands high-pH solutions during industrial fluid processing, offering durability where other polymers might degrade.
• Atmospheric Testing - Used in dry deposition sampling to capture specific atmospheric nitrates and sulfates for environmental quality studies.
• Southern Blot Transfer - Binds nucleic acids strongly during capillary transfer, providing a durable matrix for repeated hybridization cycles.
• Radiolabeled Assays - Retains radiolabeled DNA/RNA fragments efficiently, ensuring accurate quantification in molecular biology experiments.
• Gene Mapping Support - Provides a stable, charge-modified surface for DNA immobilization, facilitating precise gene mapping and analysis steps.
• Northern Blotting - Excellent for RNA transfer applications where high tensile strength is required for multiple rounds of probe stripping.