Supor 200 Membrane Disc Filters, 0.2um - 142mm, No Tab, 25/Pk SKU: 66549

Supor (PES) Membrane Filters - 66549

Designed to deliver reproducibility and confidence across critical sample types, the Pall 66549 provides the filtration consistency that method validation demands. At its core, full pH compatibility from 1 to 14 allows Supor membranes to handle acidic mobile phases, neutral buffers, and alkaline cleaning solutions without performance degradation. Taken together, consistent surface properties across the full membrane area support uniform particle capture and reliable results in gravimetric, microscopic, and culture-based analytical workflows.

Material Specifications

• Rigorous quality controls validate retention performance at rated pore sizes, positioning Supor as a primary membrane choice for critical filtration in biopharmaceutical production.
• Ultra-low protein binding preserves the biological activity of growth factors, cytokines, and other sensitive proteins during membrane passage.
• Consistent lot-to-lot performance supports standardized filtration protocols, reducing the revalidation burden when transitioning between production lots.
• Broad chemical compatibility across pH 1–14 enables Supor membranes to process acidic, neutral, and alkaline solutions without membrane degradation.
• Rated for continuous operation at temperatures reaching 55°C, enabling filtration of heated solvents and process fluids without material compromise.

When your analytical method specifies membrane filtration as a sample preparation step, the retention characteristics and extractable profiles documented above allow you to meet method requirements without additional qualification work. To support this, complete specification documentation for this device supports the traceability requirements of your quality system, providing the recorded evidence of consumable performance that auditors and method reviewers expect to see. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

51psi

Color

White

Diameter

142mm

Extractables

< 2% (Passes USP Class VI)

Filtration Area

158.37cm²

Flow Rate

26 mL/min/cm²

Grid (Yes/No)

No

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Membrane Thickness (µm)

130 – 160µm

Pack Count

25

pH Range

1-14

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Support Material

N/A

Wettability

Hydrophilic

• Diagnostic Kit Reagents - Clarifies high-value diagnostic buffers in manufacturing, ensuring lot-to-lot consistency and particle-free reagents.
• Gene Therapy Buffers - Filters large volumes of viral vector buffers with low protein binding, preserving the viral titer effectively.
• High-Speed Vac Filtration - Accelerates the processing of liters of media in vacuum cups, significantly reducing hood time for lab staff.
• Automated Media Fill - Integrated into automated media dispensing systems, providing reliable flow rates that prevent machine timeouts.
• Exosome Purification - Clarifies cell supernatants prior to exosome isolation, removing cellular debris without trapping the nanovesicles.
• Buffer Filtration - Provides fast flow rates and low protein binding, ideal for the rapid processing of laboratory buffers and solutions.