Supor (PES) Membrane Filters - 66550
Designed to deliver reproducibility and confidence across critical sample types, the Pall 66550 provides the filtration consistency that method validation demands. Asymmetric polyethersulfone construction places the tightest pore layer at the upstream membrane surface, maximizing retention efficiency while the open substructure sustains flow. In effect, from raw polymer through final inspection, the manufacturing process is designed to ensure that every membrane disc meets the performance specifications of its grade designation.
Material Specifications
- Rigorous quality controls validate retention performance at rated pore sizes, positioning Supor as a primary membrane choice for critical filtration in biopharmaceutical production.
- Broad chemical compatibility across pH 1–14 enables Supor membranes to process acidic, neutral, and alkaline solutions without membrane degradation.
- Consistent lot-to-lot performance supports standardized filtration protocols, reducing the revalidation burden when transitioning between production lots.
- Supor polyethersulfone membranes deliver the highest flow rates in the PES membrane class, reducing vacuum filtration time for high-volume laboratory applications.
- Ultra-low protein binding preserves the biological activity of growth factors, cytokines, and other sensitive proteins during membrane passage.
When your analytical method specifies membrane filtration as a sample preparation step, the retention characteristics and extractable profiles documented above allow you to meet method requirements without additional qualification work. Meeting this challenge, complete specification documentation for this device supports the traceability requirements of your quality system, providing the recorded evidence of consumable performance that auditors and method reviewers expect to see. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 51psi
- Color
- White
- Diameter
- 293mm
- Extractables
- < 2% (Passes USP Class VI)
- Filtration Area
- 674.26cm²
- Flow Rate
- 26 mL/min/cm²
- Grid (Yes/No)
- No
- Material
- Polyethersulfone (PES)
- Maximum Operating Pressure
- 75psi
- Maximum Operating Temperature (°C)
- 55°C
- Membrane Thickness (µm)
- 130 – 160µm
- Pack Count
- 25
- pH Range
- 1-14
- Pore Size (µm)
- 0.2
- Sterility
- Nonsterile
- Sterilization
- Autoclavable at 121°C for 15-20 min
- Support Material
- N/A
- Wettability
- Hydrophilic
- Exosome Purification - Clarifies cell supernatants prior to exosome isolation, removing cellular debris without trapping the nanovesicles.
- Stem Cell Media Prep - Filters viscous, growth-factor-rich media without clogging, preserving the critical nutrients needed for cell health.
- Automated Media Fill - Integrated into automated media dispensing systems, providing reliable flow rates that prevent machine timeouts.
- Gene Therapy Buffers - Filters large volumes of viral vector buffers with low protein binding, preserving the viral titer effectively.
- Bioprocess Clarification - Supor disc membranes remove fine particulates from cell culture harvests, protecting downstream purification steps.
- Diagnostic Kit Reagents - Clarifies high-value diagnostic buffers in manufacturing, ensuring lot-to-lot consistency and particle-free reagents.