Supor 450 Membrane Disc Filters, 0.45um - 293mm, No Tab, 25/Pk SKU: 66554

Supor (PES) Membrane Filters - 66554

The Pall 66554 protects sensitive instrumentation and sample integrity by providing reliable particulate removal with minimal analyte adsorption or background interference. Complementing this, full pH compatibility from 1 to 14 allows Supor membranes to handle acidic mobile phases, neutral buffers, and alkaline cleaning solutions without performance degradation. In turn, controlled production conditions produce membranes with documented pore size distribution and thickness tolerances, supporting method reproducibility across multiple filter lots.

Material Specifications

• Broad chemical compatibility across pH 1–14 enables Supor membranes to process acidic, neutral, and alkaline solutions without membrane degradation.
• Supor polyethersulfone membranes deliver the highest flow rates in the PES membrane class, reducing vacuum filtration time for high-volume laboratory applications.
• Supplied in bulk non-sterile packaging, offering an economical option for routine clarification and general laboratory filtration tasks.
• Consistent lot-to-lot performance supports standardized filtration protocols, reducing the revalidation burden when transitioning between production lots.
• Rigorous quality controls validate retention performance at rated pore sizes, positioning Supor as a primary membrane choice for critical filtration in biopharmaceutical production.

Whether your method calls for gravimetric analysis, particle visualization, or microbial enumeration, the pore consistency documented above ensures your results reflect the sample, not the filter. The documented retention specifications of this device ensure that your filtrate meets the particulate cleanliness requirements of your downstream analytical or process step without additional verification. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Color

White

Diameter

293mm

Extractables

< 2% (Passes USP Class VI)

Filtration Area

674.26cm²

Flow Rate

65 mL/min/cm²

Grid (Yes/No)

No

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Membrane Thickness (µm)

130 – 160µm

Pack Count

25

pH Range

1-14

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Support Material

N/A

Wettability

Hydrophilic

• Stem Cell Media Prep - Filters viscous, growth-factor-rich media without clogging, preserving the critical nutrients needed for cell health.
• Gene Therapy Buffers - Filters large volumes of viral vector buffers with low protein binding, preserving the viral titer effectively.
• Exosome Purification - Clarifies cell supernatants prior to exosome isolation, removing cellular debris without trapping the nanovesicles.
• Buffer Filtration - Provides fast flow rates and low protein binding, ideal for the rapid processing of laboratory buffers and solutions.
• Bioprocess Clarification - Supor disc membranes remove fine particulates from cell culture harvests, protecting downstream purification steps.
• High-Speed Vac Filtration - Accelerates the processing of liters of media in vacuum cups, significantly reducing hood time for lab staff.