Metricel Black PES Membrane Disc Filter - 0.45um, 47mm, Gridded, 100/Pk SKU: 66586

Polyethersulfone (PES) Membrane Filters - 66586

Precision-manufactured Hydrophilic membrane with a verified 0.45 pore structure delivers consistent retention performance across demanding laboratory filtration workflows. Precision-manufactured Hydrophilic membrane with a verified 0.45 pore structure delivers consistent retention across the full operating range. As a result, controlled production conditions produce membranes with documented pore size distribution and thickness tolerances, supporting method reproducibility across multiple filter lots.

Material Specifications

• Minimal background interference from extractables ensures PES membranes protect the integrity of sensitive biological preparations during filtration.
• Naturally hydrophilic, PES membranes require no pre-wetting and offer broad compatibility with aqueous buffers, alcohols, and mild organic solvents.
• Asymmetric membrane architecture concentrates the retentive layer at the surface while maintaining an open substructure for sustained high flow.
• Packaged without sterilization for applications where downstream sterility is achieved by other means or is not a process requirement.
• Polyethersulfone (PES) membranes deliver high flow rates with ultra-low protein binding, making them the preferred choice for biological sample filtration.

If your protocol requires direct on-membrane analysis by microscopy or culture, the surface characteristics and dimensional tolerances described above give you a substrate that performs consistently from disc to disc. Specifically, because PES resists fouling from protein-rich samples more effectively than cellulose-based alternatives, you can process larger volumes through a single filter before flow degradation forces a mid-batch device change. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

33psi

Color

Black

Diameter

47mm

Extractables

2% to 5%

Filtration Area

17.35cm²

Flow Rate

65 mL/min/cm²

Grid (Yes/No)

Yes

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Membrane Thickness (µm)

130 – 160µm

Pack Count

100

pH Range

1-14

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Support Material

N/A

Wettability

Hydrophilic

• Enzyme Recovery - Ensures minimal yield loss during the filtration of dilute enzyme solutions due to its inherently low-binding surface.
• TFF Cassette Production - Used as the core membrane in flat-sheet tangential flow filtration devices for protein concentration and diafiltration.
• Large Volume Processing - Filters liters of culture media in vacuum filter units, offering the fastest flow rates for routine lab preparations.
• Microarray Substrate - Provides a low-background surface for protein array printing, minimizing noise in high-throughput screening applications.
• Buffer Batching - Clarifies large batches of biological buffers in production, protecting downstream chromatography columns from fouling.
• Tissue Culture Support - Acts as a porous growth support for 3D tissue culture inserts, allowing nutrient diffusion while anchoring the cells.