Nylaflo Nylon Membrane Disc Filter - 0.45um, 47mm, 100/Pk SKU: 66608

Nylon Membrane Filters - 66608

The Pall 66608 combines a controlled pore size distribution with low extractable levels, ensuring the data accuracy that sensitive analytical methods require. Verified 0.45 pore distribution across the Hydrophilic membrane surface guarantees batch-to-batch consistency in particle capture and analyte passage. Precision manufacturing ensures that each membrane disc delivers the rated retention, flow rate, and surface consistency that analytical and microbiological methods require.

Material Specifications

• Broad compatibility with alcohols, aliphatic hydrocarbons, and aromatic solvents extends Nylon filtration into mixed-solvent sample preparation.
• Materials of construction maintain their mechanical and chemical properties at temperatures up to 55°C, supporting heated filtration protocols.
• Ideal for filtering aqueous biological solutions and mobile phases.
• Alkaline-resistant and compatible with a broad range of aqueous buffers used in pharmaceutical and biotechnology laboratories.
• Naturally hydrophilic and constructed with high tensile strength, Nylon provides reliable performance without pre-wetting in aqueous applications.

Scaling from development to routine production requires membrane consistency at every lot, and the documented specifications provide the reproducibility needed to validate the filtration step once. In this context, natural wettability lets you begin filtration immediately upon sample contact, eliminating the bubble formation and flow interruption that hydrophobic membranes introduce without pre-treatment. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Color

White

Diameter

47mm

Extractables

< 1% (HPLC Certified)

Filtration Area

17.35cm²

Flow Rate

60 mL/min/cm²

Grid (Yes/No)

No

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

55°C

Membrane Thickness (µm)

100 – 130µm

Pack Count

25

pH Range

3-14

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Non-autoclavable

Support Material

N/A

Wettability

Hydrophilic

• Radiolabeled Assays - Retains radiolabeled DNA/RNA fragments efficiently, ensuring accurate quantification in molecular biology experiments.
• Northern Blotting - Excellent for RNA transfer applications where high tensile strength is required for multiple rounds of probe stripping.
• Gene Mapping Support - Provides a stable, charge-modified surface for DNA immobilization, facilitating precise gene mapping and analysis steps.
• Solid Phase Extraction - Acts as a frit or barrier in custom extraction columns, retaining sorbent beds while allowing solvent to pass through.
• Southern Blot Transfer - Binds nucleic acids strongly during capillary transfer, providing a durable matrix for repeated hybridization cycles.
• Atmospheric Testing - Used in dry deposition sampling to capture specific atmospheric nitrates and sulfates for environmental quality studies.