Acro Disc PSF Syringe Filters w/ PVDF Membrane - GxF/0.45um, 25mm, 1000/Pk
Pall SKU: AP-4308

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - AP-4308

Quality controls spanning raw membrane casting through final device integrity testing ensure consistent performance across Pall production lots. Syringe filters mount on a syringe to clarify a sample in a single manual pass. Hydrophilic PVDF wets aqueous and HPLC samples on contact while keeping analyte adsorption low for clean recovery and clarifies samples at the rated pore size. The PP housing stays inert across common laboratory solvents and buffers in routine use while preventing sample bypass under rated operating pressure and keeps the fluid path low in extractable contamination. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Resists HPLC mobile phases, alcohols, and mild hydrocarbons
• Absolute pore size rating gives consistent results across protocols
• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Mechanically durable membrane holds integrity under filtration pressure

Housing Specifications

• Rigid polypropylene body holds its shape under manual filtration pressure
• Thermal-bonded construction keeps adhesives out of the fluid path
• Plasticizer-free polyolefin construction keeps the fluid path clean
• Resists aqueous acids, bases, and alcohols in routine sample prep

Reproducible separations start with samples that reach the column free of particulates. Pre-injection filtration protects the resolution your methods depend on by clearing particulates ahead of the column and frits. Ask our friendly customer service team to confirm the pore size, membrane, and sterility options your filtration application calls for.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

1000

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily