Pall
Acro Disc PSF Syringe Filters w/ PVDF Membrane - GxF/0.45um, 25mm Autopack Tubes (25/Pkg 200/cs) SKU: AP-4309

Polyvinylidene Difluoride (PVDF) Syringe Filters, 0.45µm, 25mm - AP-4309

Designed to protect sensitive chromatography columns from clogging, the Polyvinylidene Difluoride (PVDF) Syringe Filters delivers exceptional retention of particulates without compromising flow rates. Facilitating rapid sample turnover, the hydrophilic Polyvinylidene Difluoride (PVDF) membrane structure ensures the 0.45 rating remains consistent even under pressure. To guarantee structural reliability, each unit undergoes strict quality control to ensure the housing and membrane seal withstand standard operating pressures without leakage. The result is a filtration solution manufactured in an ISO-certified facility that minimizes distinct interference, providing clean baselines for publication-quality data.

Key Polyvinylidene Difluoride (PVDF) Membrane Characteristics

• Polyvinylidene Difluoride (PVDF) membrane with hydrophilic (hplc) / hydrophobic (venting) affinity
• Ultra-Low Protein Binding characteristics
• Excellent resistance to HPLC mobile phases, alcohols, and mild hydrocarbons
• Incompatible with acetone, DMSO, or strong bases (> pH 12)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lock/ Luer Slip for secure fitting
• 3.9cm² effective filtration area
• < 100 µl holdup volume to minimize sample loss

When you integrate these filters into your daily standard operating procedures, you are choosing a workflow that prioritizes efficiency without compromising results. Protecting your downstream processes requires a defensive strategy, and utilizing these verified filters gives you the peace of mind that your work is safe. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

144ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

25

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

Borosilicate Glass (GxF)

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wetability

Hydrophobic

• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection
• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation