Acro Disc PSF Syringe Filters w/ PVDF Membrane - GxF/0.45um, 25mm, 200/Pk
Pall SKU: AP-4310

Pall Acrodisc PVDF Syringe Filters, 0.45 µm, 25 mm, 200/Pk - AP-4310

Quality controls spanning raw membrane casting through final device integrity testing ensure consistent performance across Pall production lots. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. The hydrophilic PVDF membrane keeps analyte adsorption low for clean recovery while drawing aqueous mobile phases through without pre-wetting and resists HPLC mobile phases, alcohols, and mild hydrocarbons. Polypropylene construction resists chemical degradation from routine sample matrices while routing flow to minimize backpressure in service and maintains housing integrity through the filtration run. Where small-volume samples must reach the instrument clean, syringe filtration clears particulates in a single pass.

Technical Specifications

• Thin membrane structure sustains high flow for fast sample throughput
• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Mechanically durable membrane holds integrity under filtration pressure
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Low extractables preserve a clean chromatographic baseline

Housing Specifications

• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• Resists stress cracking from aqueous salt and buffer solutions
• Low extractable contribution protects sensitive downstream analyses
• Resists aqueous acids, bases, and alcohols in routine sample prep

Reproducible separations start with samples that reach the column free of particulates. Upstream sample clarification keeps your separations clean and reproducible so your filtrate reaches the column clean. Call on the Tisch Scientific team to standardize filtration products across your methods with volume pricing and documentation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

24psi

Burst Pressure (psi)

60psi

Connection Type

Luer-Lock/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

3.9cm²

Flow Rate

110ml

Holdup Volume

< 100 µL

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

82°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 15-20 min

Wettability

Hydrophobic

• Western Blotting - Ensures ultra-low protein binding for maximum sample recovery, critical for sensitive immunodetection protocols and assays
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays
• Trace Analysis - Prevents non-specific binding in trace analysis, ensuring that low-concentration analytes remain in solution for detection
• Spectroscopy - Provides optical clarity and low background interference, making it ideal for UV-Vis and fluorescence sample preparation
• Protein Purification - Facilitates the routine clarification of chromatography samples, preventing column fouling without binding target proteins
• Immunochemistry - Delivers exceptional chemical resistance for mild organic mixtures used in sensitive immunochemical research applications